The use of phenol as a neurolytic agent: A review

Spinal subdural haematoma as a complication of immediate epidural blood patch

“…We believe that the previous epidural phenol injections in our case may also have contributed to unusually frequent inadvertent dural punctures since epidurally injected phenol causes local tissue necrosis (in this case epidural fat) and subsequent fibrosis leading to obliteration of the epidural space at lower thoracic levels. 12 Spinal subdural haematoma with resulting cauda equina compression in patients without coagulopathy has rarely been reported in the anaesthesia literature. 13 In such patients without coagulopathy, such a spinal haematoma may be difficult to diagnose clinically since the syndrome of back pain and/or myelopathy can initiaUy be vague or mild.…”

Evaluation of benzalkonium chloride chemoneurolytic proximal gastric vagotomy

“…Pharmacologic denervation of the parietal cell mass was suggested by previous research which employed the chemoneurolysis of peripheral and autonomic nerves. Thus, phenol [13,50], cobaltous chloride [8,15], and BAC [9,14,18,29,35,36,[39][40][41]46] are three agents that have been employed successfully both experimentally in animals and to a limited extent in man for denervation mainly for pain control. Due to the perceived chemoneurolytic nonspecificity and inferiority, phenol was not considered for further experimentation [49].…”

Relief of intractable perineal pain by coccygeal nerve block in anterior sacrococcygeal ligament after surgery for rectal cancer

“…The individual anatomical differences in the sacral bone possibly cause inadequate spread of a neurolytic solution. These procedures sometimes cause complications such as sensory paralysis of the pudendum, dysuria, or weakness in the lower limbs [6][7][8].…”