The Use of patient Reported Outcome Measures for Rheumatoid Arthritis in Japan: A Systematic Literature Review

Abstract

Background:Patient-reported outcomes (PRO) obtained through routine medical care may identify patients’ day-to-day burden and help tackle the disease from the patients’ perspective. However, there is a paucity of information regarding the availability of PRO data and PRO tools for rheumatoid arthritis (RA) in Japan.Objective: We reviewed the literature on PRO data availability and to identify PRO measures implemented in Japan for RA patients. Method: We conducted a systematic literature review using ICHUSHI and the PubMed databases on PRO measures for RA published from January 2011 to August 2015 in Japan.Results:After removing duplicates, 2423 manuscripts were found. From these, 100 manuscripts were included for review and analysis. We found 29 PRO tools that were used to assess various domains of health such as general well-being, pain, functionality, and fatigue. More than 90% of the studies utilized PRO tools for research purpose. Only one study reported PRO tool implementation in the routine medical care.Conclusion:The importance of PROs is recognized in Japan. PRO tools varied significantly and were mostly used for research purposes, while reports on the use of PRO measures in routine medical care were limited. Despite the awareness of PROs in the research community, unmet needs remain among RA patients in Japan. Further work is needed to investigate ways in which PROs can better reflect these unmet needs and be utilized in routine medical care.

The acceptability of implementing patient‐reported measures in routine maternity care: A systematic review

“…According to the studies, stakeholders were generally positive about the implementation of PRMs in maternity care, recognized the potential benefits and supported the systematic integration of PRMs into routine clinical practice. This main finding was consistent with other reviews that studied the acceptability of using and implementing PRMs in other clinical contexts outside maternity care 19,45,46 …”

“…This main finding was consistent with other reviews that studied the acceptability of using and implementing PRMs in other clinical contexts outside maternity care. 19,45,46 According to included studies, women's acceptance of PRMs as an integrated part of maternity care could vary with timing, modes, and platforms of PRMs administration. While some studies reported that women expressed their preference for and satisfaction with digital responses to PRMs questions, 21,24,27,29,32 synthesized data from other studies suggested that women were more likely to respond to paper-based questionnaires than web-or app-based ones.…”

The Use of Oral Analgesics and Pain Self-Efficacy Are Independent Predictors of the Quality of Life of Individuals with Rheumatoid Arthritis

“…Rheumatoid arthritis (RA) is a chronic, progressive, systemic inflammatory autoimmune disease that causes joint deformity, pain, and functional disability [1,2]. RA affects approximately 0.5-1% of the population globally [3].…”

Relationship between disease activity and patient-reported outcomes in rheumatoid arthritis: Post hoc analyses of overall and Japanese results from two phase 3 clinical trials

“…To date, however, there have been no reports on residual symptoms as indicated by PROs among patients achieving remission or LDA after previous inadequate responses to MTX, or in Japanese patients achieving remission or LDA. Further, there are relatively limited data available in general about PROs in Japanese patients with RA [21]. Having a better understanding of residual symptoms and how disease activity relates to PROs in these patients, including those from different populations with different cultural norms that could affect responses, may help facilitate better treatment strategies.…”