This research was conducted to determine the effect of inulin on the efficiency of feed utilization and the hematological parameters of red tilapia. This study used a completely randomized design (CRD), with 4 treatments and 3 replications. The doses of inulin used in the treatment were 0,00 g/kg, 1,00 g/kg, 2,00 g/kg and 4,00 g/kg. Tilapia with body length of 6,00-6,50 cm and weight of 4,00-4,50 g were reared in a plastic container with a volume of 40 l of water in a semi-closed water recirculation system for 30 days. Fish were fed with treatment using the at satiation method with a frequency of 3 times a day. The results showed that the administration of inulin had no effect on the efficiency of feed utilization (p>0,05), but gave the best value on hemoglobin levels, hematocrit levels, total erythrocytes, total leukocytes, lymphocyte levels, monocyte levels, and neutrophil levels at dose 2,00 g/kg (p<0,05).