The Use of Microvolt T-Wave Alternans in Chagas Disease

Pastore, Carlos Alberto

doi:10.5935/abc.20180081

Cited by 2 publications

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References 18 publications

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“…Those abnormalities were related to death [ 9 , 21 ] and the progression to heart failure [ 21 ]. The ChD group also had an important incidence of premature beats and major Q waves abnormalities related to death in other cohorts [ 22 , 23 , 24 ]. Although low voltage is an established ECG abnormality related to the mortality in the general population with ChD [ 1 ], it was not included in the analyzes because it is not a major electrocardiographic abnormality of the Minnesota code.…”

Section: Discussionmentioning

confidence: 99%

The evolution of electrocardiographic abnormalities in the elderly with Chagas disease during 14 years of follow-up: The Bambui Cohort Study of Aging

et al. 2023

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Background The natural history of Chagas disease (ChD) in older ages is largely unknown, and it is a matter of controversy if the disease continues to progress in the elderly. Objective To investigate the evolution of electrocardiographic abnormalities in T. cruzi chronically infected community-dwelling elderly compared to non-infected (NChD) subjects and how it affects this population’s survival in a follow-up of 14 years. Methods and results A 12-lead ECG of each individual of the Bambui Cohort Study of Aging was obtained in 1997, 2002, and 2008, and the abnormalities were classified using the Minnesota Code. The influence of ChD on the ECG evolution was assessed by semi-competing risks considering a new ECG abnormality as the primary event and death as the terminal event. A Cox regression model to evaluate the population survival was conducted at a landmark point of 5.5 years. The individuals of both groups were compared according to the following categories: Normal, Maintained, New, and More by the development of ECG major abnormalities between 1997 and 2002. Among the participants, the ChD group had 557 individuals (median age: 68 years) and NChD group had 905 individuals (median age: 67 years). ChD was associated with a higher risk of development of a new ECG abnormality [HR: 2.89 (95% CI 2.28–3.67)]. The development of a new major ECG abnormality increases the risk of death ChD patients compared to those that maintain a normal ECG [HR: 1.93 (95% CI 1.02–3.65)]. Conclusion ChD is still associated with a higher risk of progression to cardiomyopathy in the elderly. The occurrence of a new major ECG abnormality in ChD patients predicts a higher risk of death.

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Section: Discussionmentioning

confidence: 99%

The evolution of electrocardiographic abnormalities in the elderly with Chagas disease during 14 years of follow-up: The Bambui Cohort Study of Aging

et al. 2023

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“…Возникающая дискордантная альтернация образует субстрат, создающий условия для блока проведения импульса; при этом активация круга ре-ентри может быть легко инициирована экстрасистолой [23]. Доказанной является связь ВСС с едва уловимыми изменениями зубца Т на микроскопическом, или микровольтном, уровне (микровольтная альтернация Т волны), для выявления и анализа которых применяются сложные сигнал-преобразующие методики [24], что не позволяет сделать эту методику рутинной.…”

Section: анатомический и электрофизиологический субстрат вссunclassified

Risk stratification of sudden cardiac death in heart failure patients: is left ventricular ejection fraction alone sufficient?

et al. 2021

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Илов Н. Н.*-к.м.н., доцент кафедры сердечно-сосудистой хирургии, врачсердечно-сосудистый хирург отделения хирургического лечения сложных нарушений ритма сердца и электрокардиостимуляции, ORCID: 0000-0003-1294-9646, Пальникова О. В.-врач-кардиолог отделения хирургического лечения сложных нарушений ритма сердца и электрокардиостимуляции, ORCID: 0000-0002-4476-5174, Стомпель Д. Р.-зав. отделением функциональной диагностики, ORCID: 0000-0002-2400-8045, Николаева Е. В.-зав. отделением лучевой диагностики, ORCID: 0000-0001-5701-2449, Нечепуренко А. А.-к.м.н., зав. отделением хирургического лечения сложных нарушений ритма сердца и электрокардиостимуляции, ORCID: 0000-0001-5722-9883.

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The Use of Microvolt T-Wave Alternans in Chagas Disease

Cited by 2 publications

References 18 publications

The evolution of electrocardiographic abnormalities in the elderly with Chagas disease during 14 years of follow-up: The Bambui Cohort Study of Aging

The evolution of electrocardiographic abnormalities in the elderly with Chagas disease during 14 years of follow-up: The Bambui Cohort Study of Aging

Risk stratification of sudden cardiac death in heart failure patients: is left ventricular ejection fraction alone sufficient?

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