The use of laser-induced fluorescence or ultraviolet detectors for sensitive and selective analysis of tobramycin or erythropoietin in complex samples

Ahmed, Hytham M.; Ebeid, Wael B.

doi:10.1016/j.saa.2015.02.025

Cited by 15 publications

(11 citation statements)

References 56 publications

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“…Laser-induced fluorescence (LIF) is another type of optical detection approach, which is broadly used for the microfluidic immunosensor design [81,82]. Recently, LIF microfluidic chips have been used in many research fields including labon-chip [83], POC testing [84,85], and organic compound analysis [86].…”

Section: Optical and Piezoelectric Biosensorsmentioning

confidence: 99%

Serological and molecular rapid diagnostic tests for Toxoplasma infection in humans and animals

Khan

Noordin

2019

Eur J Clin Microbiol Infect Dis

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Infection by Toxoplasma gondii is prevalent worldwide. The parasite can infect a broad spectrum of vertebrate hosts, but infection of fetuses and immunocompromised patients is of particular concern. Easy-to-perform, robust, and highly sensitive and specific methods to detect Toxoplasma infection are important for the treatment and management of patients. Rapid diagnostic methods that do not sacrifice the accuracy of the assay and give reproducible results in a short time are highly desirable. In this context, rapid diagnostic tests (RDTs), especially with point-of-care (POC) features, are promising diagnostic methods in clinical microbiology laboratories, especially in areas with minimal laboratory facilities. More advanced methods using microfluidics and sensor technology will be the future trend. In this review, we discuss serological and molecular-based rapid diagnostic tests for detecting Toxoplasma infection in humans as well as animals.

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Section: Optical and Piezoelectric Biosensorsmentioning

confidence: 99%

Serological and molecular rapid diagnostic tests for Toxoplasma infection in humans and animals

Khan

Noordin

2019

Eur J Clin Microbiol Infect Dis

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“…The handling of minute samples is difficult, and thus this mode is applied when ample volumes of samples and reagents are available. Pre‐capillary mode was the most commonly applied procedure accounting for 2/3 or 29 of the 46 covered articles .…”

Section: Derivatisation Modesmentioning

confidence: 99%

“…This is often the case for fluorescence detection where native fluorescence is rather uncommon and only the labelled species provide a strong signal. There were 24 articles on LIF , 16 on UV , 3 on electrochemical detection , and 4 on MS . In MS detection, derivatisation was used to improve the separation (see Section ) and to enable MS detection in favourable positive ion ESI mode .…”

Section: Derivatisation For Detectionmentioning

confidence: 99%

“…Amine derivatisation was applied for amino acids , proteins , drugs , biomarkers , and aliphatic amines . The derivatisation agents for amino acids were fluorescamine, fluorescein isothiocyanate (FITC), NDA, OPA, 3‐(4‐carboxybenzoyl)quinolone‐2‐carboxaldehyde (CBQCA), FACE‐SH, 3‐(2‐furoyl)quinoline‐2‐carboxaldehyde (FQ), 4‐chloro‐7‐nitrobenzofurazan (NBD‐Cl), FluoProbes®488‐NHS, and 5‐carboxyfluorescein succinimidyl ester (CFSE).…”

Section: Derivatisation For Detectionmentioning

confidence: 99%

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Derivatisation for separation and detection in capillary electrophoresis (2015–2017)

Wuethrich

Quirino

2017

Electrophoresis

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Derivatisation is an integrated part of many analytical workflows to enable separation and detection of the analytes. In CE, derivatisation is adapted in the four modes of pre-capillary, in-line, in-capillary, and post-capillary derivatisation. In this review, we discuss the progress in derivatisation from February 2015 to May 2017 from multiple points of view including sections about the derivatisation modes, derivatisation to improve the analyte separation and analyte detection. The advancements in derivatisation procedures, novel reagents, and applications are covered. A table summarising the 46 reviewed articles with information about analyte, sample, derivatisation route, CE method and method sensitivity is provided.

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“…This is due to the polar basic nature and the lack of UV absorbing chromophore in the molecule. Several methods have been described to determine tobramycin by adsorptive stripping voltammetric method (Sun et al, 2005), electrophoresis capillary (El-Attug et al, 2012;Ahmed and Ebeid, 2015) and ion pair LC methods (Hankoand Rohrer, 2006;Szúnyog et al, 2000;Valentini et al, 2008;Hanko et al, 2008;Chopra et al, 2010). A literature survey revealed some reversed phase liquid chromatographic methods for the quantitation of tobramycin employing mass detector (Keevil et al, 2003;Guo et al, 2006), ELSD (Megoulas et al, 2005;Pfeifer et al, 2015) and PED (Manyanga et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

Determination of the Chemical Stability of Various Formulations of Tobramycin Eye-Drops by HPLC Method and Data Analysis by R-GUI Stability Software

Rosasco¹,

Segall

2015

J App Pharm Sci

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Tobramycin, is a water soluble aminoglycoside antibiotic produced by the fungus Streptomyces tenebrarius and used in a variety of pharmaceutical applications including ophthalmic solutions, suspensions and ointments; inhalation solutions and intravenous administration. There are commercially available eye drops formulations in the Argentinian market that have different conservation conditions. We formulated six eye drops solutions, studied their stability at 2-8°C, 25°C, and 40°C, 75% RH and quantified using USP method. Only half of the formulations studied were found to be stable for two years at ambient temperature which is their expected expiry date and only one for three years in the same condition. One system was unstable in the three conservation conditions studied, including appearance and pH.

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The use of laser-induced fluorescence or ultraviolet detectors for sensitive and selective analysis of tobramycin or erythropoietin in complex samples

Cited by 15 publications

References 56 publications

Serological and molecular rapid diagnostic tests for Toxoplasma infection in humans and animals

Serological and molecular rapid diagnostic tests for Toxoplasma infection in humans and animals

Derivatisation for separation and detection in capillary electrophoresis (2015–2017)

Determination of the Chemical Stability of Various Formulations of Tobramycin Eye-Drops by HPLC Method and Data Analysis by R-GUI Stability Software

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