The use of expanded criteria cadaver and live donor kidneys for transplantation

Modlin, Charles S.; Goldfarb, David A.; Novick, Andrew C.

doi:10.1016/s0094-0143(01)80026-4

Cited by 27 publications

(12 citation statements)

References 116 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…These findings are in line with a previous report of worse survival of grafts from NHB donors over 60 years in Japan (14). Apparently, older kidneys suffer more ischemia reperfusion injury than younger kidneys, probably due to reduced functional nephron mass, atherosclerotic lesions and reduced regenerative capacity associated with greater age (6,18). Therefore, transplant outcome could potentially have been improved by reducing the prolonged cold ischemic times observed in our series.…”

Section: Discussionsupporting

confidence: 93%

Kidney Transplantation Using Elderly Non-Heart-Beating Donors: A Single-Center Experience

Snoeijs

Schaefer

Christiaans

et al. 2006

American Journal of Transplantation

View full text Add to dashboard Cite

Although acceptable outcomes have been reported in both non-heart-beating (NHB) and elderly donors individually, the large pool of elderly NHB donors has not yet been fully utilized. In 1994, we expanded our transplant protocol to include NHB donors aged over 65 years and this study compares the clinical outcomes with regular NHB transplantations. Up to June 2005, 24 patients were transplanted at our center with kidneys from NHB donors aged 65 years or more, whereas 176 patients received grafts from conventional NHB donors during the same period. Grafts from older donors were associated with inferior glomerular filtration rates (29 vs. 44 mL/min after 1 year, p = 0.01) and graft survival (52% vs. 68% after 5 years, p = 0.19) compared to younger NHB donor grafts, although the difference in graft survival was not statistically significant. Exclusion of older NHB donor kidneys with severe vascular pathology resulted in similar graft survival of older and younger NHB donor kidneys. We conclude that the use of elderly NHB donors in order to expand the donor pool was associated with unacceptable clinical outcomes and cannot be justified without further refinement in their selection, for example, by histological assessment of pretransplant biopsies.

show abstract

Section: Discussionsupporting

confidence: 93%

Kidney Transplantation Using Elderly Non-Heart-Beating Donors: A Single-Center Experience

Snoeijs

Schaefer

Christiaans

et al. 2006

American Journal of Transplantation

View full text Add to dashboard Cite

show abstract

“…A s increasing numbers of patients with end-stage renal failure are considered candidates for kidney transplantation, a significant shortfall in the number of cadaveric kidneys available for donation has become a problem (1). Living donor nephrectomy has been developed and promoted as a method to address the shortfall in kidneys available for transplantation.…”

mentioning

confidence: 99%

A Systematic Review of Laparoscopic Live-Donor Nephrectomy

Tooher

Rao²,

Scott³

et al. 2004

Transplantation

140

View full text Add to dashboard Cite

show abstract

“…Actualmente, a pesar de ser España el primer país en donación de órganos procedentes de cadáver, sigue siendo la escasez de riñones la principal causa de muerte para los pacientes en lista de espera 14 . Sin duda la potenciación de la donación de vivo podría reducir de manera importante la lista de espera, ya que en nuestro país se encuentra claramente infrautilizada.…”

Section: Discussionunclassified

Donante vivo renal: Experiencia de cirugía abierta y laparoscópica. Hospital La Paz

et al. 2009

View full text Add to dashboard Cite

ResumenLa extracción renal laparóscopica es una técnica escasamente implantada en nuestro país, debido principalmente a la dificultad técnica que supone y a la gran cantidad de donante cadáver que encontramos en nuestro medio. Presentamos y analizamos nuestra serie de donante vivo abierto y laparoscópico desde 1984. Material y Métodos: Desde 1984 hasta 2007 se han realizado 84 extracciones renales de donante vivo; 64 por cirugía abierta, 20 laparoscópicas. El abordaje transperitoneal ha sido el elegido en el caso de la laparoscopia y la lumbotomía en la abierta. Resultados: En la técnica abierta el tiempo quirúrgico medio es de 112 min (70-155), el tiempo medio de isquemia caliente es de 20 segundos (15-47) y la estancia media es de 4,8 días (3-9). En los casos realizados por laparoscopia, el tiempo quirúrgico medio es de 146 min (90-210), el tiempo de isquemia caliente es de 3 min y 15 seg (2-3,25) y la estancia media es de 3,4 días (2-9). Conclusiones: El abordaje laparoscópico es una técnica que no está exenta de riesgos y que no deben ser despreciados. Debe ser realizado por equipos con experiencia en cirugía renal laparoscópica. En lo referente al riñón obtenido de donante vivo, sin duda se trata de una magnífica solución para pacientes en estado de insuficiencia renal crónica. Es un recurso que deben ofrecer los principales hospitales de nuestro país. 4,8 days (3-9). Laparoscopic cases, the operating time is 146 min (90-210), ischaemia time 3 min 15 sec (2-3,25 min) and postoperative hospital stay 3,4 days (2-9). Conclusions: The laparoscopic live donor nephrectomy is a difficult and demanding technique. It should be done by experienced team in laparoscopic renal surgery. The kidney from a live donor is a very good alternative for the cronic renal failure. It should be offered in our main hospitals.

show abstract

The use of expanded criteria cadaver and live donor kidneys for transplantation

Cited by 27 publications

References 116 publications

Kidney Transplantation Using Elderly Non-Heart-Beating Donors: A Single-Center Experience

Kidney Transplantation Using Elderly Non-Heart-Beating Donors: A Single-Center Experience

A Systematic Review of Laparoscopic Live-Donor Nephrectomy

Donante vivo renal: Experiencia de cirugía abierta y laparoscópica. Hospital La Paz

Contact Info

Product

Resources

About