The use of corticosteroids and nonsteroidal antiinflammatory medication for the management of pain and inflammation after third molar surgery: A review of the literature

Kim, King; Brar, Pardeep; Jakubowski, J; Kaltman, Steven; Lopez, Eustorgio

doi:10.1016/j.tripleo.2008.11.005

Cited by 187 publications

(172 citation statements)

References 29 publications

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“…Glucocorticoids are effective in each step of inflammation process and subsequent decrease in capillary dilation, circulating lymphocytes, fibroblast proliferation and prostaglandin and leukotriene inhibition. Most single dose glucocorticoid drugs used in oral surgeries are not effective for more than 24 h, so for maintaining their antiinflammatory effects they should be taken for a minimum NS not significant of 3 and maximum of 5 days for gaining the maximum efficiency and minimum risk of delayed healing and suppression of HPA axis [5]. It is possible that combining the both drug typesNSAIDs and glucocorticoid drugs-will be more efficient in post-operative management of complications [12,[16][17][18].…”

Section: Discussionmentioning

confidence: 99%

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A Comparative Study of the Effect of Prednisolone and Celecoxib on MMO (Maximum Mouth Opening) and Pain Following Removal of Impacted Mandibular Third Molars

Moghaddamnia

Nosrati

Mehdizadeh

et al. 2012

J. Maxillofac. Oral Surg.

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Objective The purpose of this study was to compare the effects of prednisolone and celecoxib on pain and maximum mouth opening (MMO) after surgical removal of mandibular third molars. Methods and Materials This double-blind clinical study was conducted upon 60 subjects. These patients received 4 tablets of either 100 mg celecocxib or 5 mg prednisolone: one tablet before surgery and the rest for every 8 h postoperation. The subjects were asked to take acetaminophen codeine as rescue dose. Interincisal distance of upper and lower central teeth and pain measurements (according to Visual Analogue Scale) were taken before surgery, 24 h, 48 h and 7 days after surgery. Results Average pain intensity in 24 h after surgery in patients receiving celecoxib was 3.6 ± 2.5 with significant difference to the other group (p = 0.041), but in subsequent evaluations prednisolone group reported less pain intensity, but the differences were not significant. MMO in 48 h after surgery was lower in prednisolone group (p = 0.640) and in further evaluations the groups were almost similar. Analyzing the data revealed no significant difference between groups in MMO. Conclusion According to this study there is no significant difference in the effects of prednisolone or celecoxib upon MMO, while celecoxib had better results for pain relief in 24 h after surgery in comparison to prednisolone.

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Section: Discussionmentioning

confidence: 99%

“…Inhibiting the cyclooxygenase path is the mechanism of action of NSA-IDS while glucocorticoids restrain production of acid arachidonic by inhibiting the phospholipase A2 enzyme [5]. COX-2 is considered as the main isoenzyme in producing pro-inflammatory prostaglandins [3].…”

Section: Introductionmentioning

confidence: 99%

A Comparative Study of the Effect of Prednisolone and Celecoxib on MMO (Maximum Mouth Opening) and Pain Following Removal of Impacted Mandibular Third Molars

Moghaddamnia

Nosrati

Mehdizadeh

et al. 2012

J. Maxillofac. Oral Surg.

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“…Any osteotomy, which involves the reflection of a full thickness mucoperiosteal flap, leads to varying degrees of post-operative swelling. An extensive swelling can compromise the surgical outcome as well as patient recovery and the airway [1].…”

Section: Introductionmentioning

confidence: 99%

“…Several methods to control the immediate inflammatory response associated with head and neck surgery have been described and used, including the use of drugs such as analgesics [1][2][3], corticosteroids [3], antibiotics [4], and proteolytic enzymes [5], laser application [6], or physical therapeutic methods like cryotherapy [7] or manual lymph drainage (MLD) [8]. No single modality of management significantly prevents and/or significantly reduces the occurrence of swelling, pain and trismus without potential undesirable side effects.…”

Section: Introductionmentioning

confidence: 99%

Influence of Kinesiologic Tape on Post-operative Swelling After Orthognathic Surgery

Tozzi

Santagata

Sellitto

et al. 2015

J. Maxillofac. Oral Surg.

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Introduction Orthognathic surgery involves making several osteotomies that lead to varying degrees of post-operative swelling. The use of KT may be beneficial for postoperative treatment after head and neck surgery, accelerating drainage of tissue reaction or haemorrhages. The goal of this study was to find out if the application of KT prevents or improves swelling, pain and trismus after orthognathic surgery, improving patients' postoperative quality of life. Materials and Methods In this double-blinded, randomized, control trial, 24 patients in whom bimaxillary orthognathic surgery was indicated, were included. Before surgery each patient alternatively was randomly included in the study group (treated with K-Taping Ò and corticosteroid) or in the control group (treated with corticosteroid). In the present study a MakerBot Ò Digitizer 3D TM was used to assess accurate volume measurements. All swelling measurements were expressed as total 3-D area of the landmarks (cm 2 ) in T0 pre-operative, T1 fourth day after surgery. Results The differences T0-T1 are highly significant (p \ 0.01) between group 1 or study group (treated with K-taping Ò ) and group 2 (control group). Discussion The use of KT appears promising, because it is simple to carry out, less traumatic, economical, can be performed everywhere in the world, free from side effects on the body. Even when swelling persists, KT gives patients the impression of a minor swelling detracting them from their pain and morbidity. Further studies have to be performed to find out if KT can reduce or replace the need for additional medications such as the use of steroids.

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“…Pain, edema, and trismus after the extraction of impacted third molars are expected outcomes and these complications adversely affect the daily life of patients (17,18,19). Many studies have suggested that corticosteroids, different anesthetics, pain killers, and anti-inflammatory drugs may reduce the severity of these complications (20,21).…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Complications Following Impacted Mandibular Third Molar Extraction in Patients with Different Hand Preference

Akyol¹,

Keçecioğlu²

2018

meandros

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Objective: Individual preference of using right or left hand for doing various hand workings, is the most easily observable form of the cerebral lateralization. It was stated that, among the right or left hand dominant individuals, there is an immunological asymetry, and a difference in motor control, visuospatial skills, and in the incidence of a number of disease. The aim of the study was to investigate pain, edema, trismus following the mandibular third molar extraction in patients with different hand preference. Amaç: Bireyin çesitli el işlerini yapmak için sağ veya sol elini tercih etmesi serebral lateralizasyonun en kolay gözlenebilen şeklidir. Sağ veya sol eli dominant olan kişiler arasında motor kontrol, vizyospasyal görevleri yerine getirmede, çeşitli hastalıkların görülme insidansında farklılıklar ve immün asimetri olduğu söylenmiştir. Bu çalışmada, mandibular 3. molar çekimini takiben görülen ağrı, ödem, trismusun el tercihi farklı olan hastalarda değerlendirilmesi amaçlanmıştır. Gereç ve Yöntemler: Çalışmaya, sağ ve sol mandibular gömülü üçüncü molar dişlerin çekiminin gerekli olduğu 43 hasta dahil edildi. Aynı hastadan sağ ve sol mandibular gömülü diş çekimi 30 gün arayla yapıldı. 4 hasta grubu oluşturuldu; 1) El tercihi sol-sağ (sağ mandibular 3.molar dişi çekilen) 2) El tercihi sol-sol 3) El tercihi sağ-sağ 4) El tercihi sağ-sol. Ağrı, ödem ve trismusun operasyondan önce ve sonra karşılaştırılması için ölçümler yapıldı.

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The use of corticosteroids and nonsteroidal antiinflammatory medication for the management of pain and inflammation after third molar surgery: A review of the literature

Cited by 187 publications

References 29 publications

A Comparative Study of the Effect of Prednisolone and Celecoxib on MMO (Maximum Mouth Opening) and Pain Following Removal of Impacted Mandibular Third Molars

A Comparative Study of the Effect of Prednisolone and Celecoxib on MMO (Maximum Mouth Opening) and Pain Following Removal of Impacted Mandibular Third Molars

Influence of Kinesiologic Tape on Post-operative Swelling After Orthognathic Surgery

Evaluation of Complications Following Impacted Mandibular Third Molar Extraction in Patients with Different Hand Preference

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