The use of chlorhexidine

Minimizing human infection from Escherichia coli O157:H7 using GUMBOS

“…32 Research from previous antibacterial studies has shown that the presence of other anionic salts and detergents antagonizes the antibacterial activity of chlorhexidine salts. 33 This was also found in our antibacterial results consisting of the stoichiometric mixtures of chlorhexidine diacetate and sodium ampicillin. This implies that anionic ampicillin can also interfere with chlorhexidine activity when used as an unreacted mixture.…”

Effect of antimicrobial soap containing chlorhexidine on the microbial flora of skin

“…Groin. In contrast to the axilla, gram-negative rods increased when the subject changed to the chlorhexidine scrub; in the controls the gram-negative rods were not detected after 4 months of treatment (P = 0.0623). Thus, the controls demonstrated fewer gram-negative rods in the axilla and groins than did the chlorhexidine-treated subjects.…”

“…The antimicrobial agent chlorhexidine has been available for use in skin antisepsis in England and Europe for 20 years. Besides being active against gram-positive organisms, chlorhexidine also displays activity against gramnegative organisms and yeasts (4,6). This study was designed to measure effects on cutaneous microbial ecology during the long-term use of a nonionic detergent solution containing 4% chlorhexidine gluconate (Hibiclens).…”

Antimicrobial Activity of Chlorhexidine Gluconate Against Natural and Artificial Contamination During Simulation of in-use Conditions

“…Chlorhexidine has excellent antimicrobial activity against Grampositive and Gram-negative bacteria (1)(2)(3)(4)(5)(6). Due to its broad-spectrum antimicrobial activities, chlorhexidine preparations have become widely used for disinfection.…”