The use of amniotic membrane in reducing adhesions after strabismus surgery

Severe fibrosis of extraocular muscles after the use of lyophilized amniotic membrane in strabismus surgery

“…One of these is the amniotic membrane. 5,7 Yamada and colleagues 7 successfully treated fat adherence syndrome after retinal surgery using amniotic membrane. Sheha and colleagues 5 used cryopreserved amniotic membrane as an adjunct in a strabismus reoperation to correct a consecutive exotropia: the muscles were wrapped with a 5 Â 15-mm segment of cryopreserved amniotic membrane, oriented with the stromal side toward the muscle.…”

Amniotic membrane in the management of strabismus reoperations

“…Amniotic membrane in strabismus 243 AM in complicated strabismus cases presented case reports or case series instead of control group studies [11][12][13]. The results of the previous experimental and clinical studies and those of our study suggest that there may be a role for AM in the management of strabismus reoperations [26].…”

“…The cause of fibrosis was not clearly identified in this study, but it was clear that lyophilized AM was ineffective in protecting against its development, although cryopreserved AM was successfully used by the same surgical technique for this purpose [11]. In our series, fresh AM was used to reduce fibrosis and restrictions, and none of the patients suffered from the complication indicated by Kassem et al…”

“…The results show that AM has an antifibrotic effect and an effective role in the prevention of adhesion formation with possible physical barrier action [24]. A case report describing the use of AM to reduce adhesion formation in a patient with consecutive esotropia and limited duction showed possible benefits of this procedure [11].…”

“…Yamada et al published a case report on the successful treatment of restrictive strabismus occurring after retinal detachment surgery, Sheha et al described wrapping the extraocular muscles (EOM) with AM in a case of consecutive exotropia, and Kersey and Vivian used AM in conjunction with mitomycin C in two patients with complex strabismus surgery [10][11][12]. Strube et al reported a case series describing the use of AM transplant to repair restrictive strabismus occurring after a variety of anterior segment, oculoplastic and retinal surgeries [13].…”