The Use of 2 Bioabsorbable Barrier Membranes in the Treatment of Interproximal Intrabony Periodontal Defects

Mattson, John S.; Gallagher, Steven J.; Jabro, M H

doi:10.1902/jop.1999.70.5.510

Cited by 31 publications

(18 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Several researchers have reported a correlation between IPD and CAL gain (1,41,76). Laurell et al performed a correlation analysis on articles which presented individual data for each subject within the research population (1).…”

Section: Relationships Of the Initial Probing Depths To The Cal Gainsmentioning

confidence: 99%

Non-bioabsorbable vs. bioabsorbable membrane: assessment of their clinical efficacy in guided tissue regeneration technique. A systematic review

et al. 2009

Self Cite

View full text Add to dashboard Cite

In a 1998 review article, Laurell andcolleagues performed a meta-analysis of relevant guided tissue regeneration (GTR) articles over the previous 20 years (1). The purpose of the present research was to expand on that work, particularly searching for trends discriminating between bioabsorbable and nonbioabsorbable barriers, as well as the use of enamel matrix derivative, with respect to interproximal bony defects. The most recent periodontal journals were reviewed and a search of PubMed (National Institutes of Health) was conducted via the internet covering 1990 to the present. Forty-nine articles were found to be relevant and within established parameters. The data were analyzed using (a) a variation of the methods described in Laurell et al.

show abstract

Section: Relationships Of the Initial Probing Depths To The Cal Gainsmentioning

confidence: 99%

Non-bioabsorbable vs. bioabsorbable membrane: assessment of their clinical efficacy in guided tissue regeneration technique. A systematic review

et al. 2009

Self Cite

View full text Add to dashboard Cite

show abstract

“…The ultimate goal of periodontal treatment is the regeneration of the supporting tissues lost due to periodontal disease [1]. Regeneration refers to the reproduction or reconstitution of a lost or injured part, in contrast to repair, which describes the healing by tissues that do not fully restore the architecture or the function of the lost part [2].…”

Section: Introductionmentioning

confidence: 99%

Local application of hyaluronan gel in conjunction with periodontal surgery: a randomized controlled trial

et al. 2011

View full text Add to dashboard Cite

Hyaluronic acid application has been proven to be beneficial in a number of medical disciplines. The aim of the current study was to clinically evaluate the effect of local application of hyaluronan gel in conjunction with periodontal surgery. Fourteen patients with chronic periodontitis having four interproximal intrabony defects (≥3 mm) with probing depth values >5 mm were included in this split-mouth study. Following initial nonsurgical periodontal therapy and re-evaluation, defects were randomly assigned to be treated with modified Widman flap (MWF) surgery in conjunction with either 0.8% hyaluronan gel (test) or placebo gel (control) application. Clinical attachment level (CAL), probing depth (PD), gingival recession (GR), plaque index (PI), and bleeding on probing (BOP) values were taken at baseline and 3 and 6 months. Differences between test and control sites were evaluated using a Wilcoxon signed-rank and a McNemar test. A Friedman and a Cochran test were used to test equal ranks over time. Statistically significant differences were noted for CAL and GR (P < 0.05) in favor of the test sites. No significant differences were found regarding PD, BOP, or PI values (P > 0.05). Hyaluronan gel application in conjunction with periodontal surgery appears to result in significant improvement of CAL and in a reduction in GR. Hyaluronan gel application appears to improve the clinical outcome of MWF surgery.

show abstract

“…12,14,15 Based on the principles of cell and developmental biology and biomaterials engineering, tissue bioengineering combines life sciences and materials research to create new tissues or organs to replace damaged or lost structures. 16,17 Tissue engineering techniques have been used successfully in regenerating bone, cartilage, muscle, and other connective tissues.…”

Section: Introductionmentioning

confidence: 99%

Cementum engineering with three‐dimensional polymer scaffolds

Jin

Zhao

Webb

et al. 2003

J Biomedical Materials Res

View full text Add to dashboard Cite

Cloned cementoblasts (OCCMs), periodontal ligament fibroblasts (SV-PDLs), and dental follicle (SV-F) cells obtained from mice were used as a tool to study periodontal tissue engineering. OCCM, SV-PDL, and SV-F cells were seeded onto three-dimensional poly lactic-co-glycolic acid (PLGA) scaffolds and cultured with the use of bioreactors or implanted subcutaneously in severe combined immune deficiency (SCID) mice for up to 6 weeks. We explored the behavior of these cells in porous PLGA sponges by cell growth, expression of mineral-associated genes using reverse transcriptase polymerase chain reaction, and mineralization by histologic analysis in vitro and in vivo. Results indicated that cells attached to PLGA scaffolds under either static or dynamic conditions in vitro. Only OCCM implants, retrieved from both in vitro bioreactors and SCID mice at 3-and 6-weeks post-cell implantation exhibited mineral formation. Types I and XII collagens, osteocalcin, and bone sialoprotein genes were detected in all implants retrieved from SCID mice. These results suggest that delivery of selected cells via PLGA scaffolds may serve as a viable approach for promoting periodontal tissue regeneration.

show abstract

The Use of 2 Bioabsorbable Barrier Membranes in the Treatment of Interproximal Intrabony Periodontal Defects

Abstract: The data indicated the bioabsorbable collagen and copolymer membranes resulted in comparable results. A larger sample size would be necessary to determine if one membrane was superior to the other.

Cited by 31 publications

References 37 publications

Non-bioabsorbable vs. bioabsorbable membrane: assessment of their clinical efficacy in guided tissue regeneration technique. A systematic review

Non-bioabsorbable vs. bioabsorbable membrane: assessment of their clinical efficacy in guided tissue regeneration technique. A systematic review

Local application of hyaluronan gel in conjunction with periodontal surgery: a randomized controlled trial

Cementum engineering with three‐dimensional polymer scaffolds

Contact Info

Product

Resources

About