The Use of 16.16‐dimethyl‐PGEl‐ A‐methyl ester (Cervagem) Vaginal Pessaries for Cervical Dilatation Prior to Evacuation for Second Trimester Termination

Bennett, Mark J.; .Horrowitz, S. D.; Wass, Debbie M.

doi:10.1111/j.1479-828x.1991.tb02763.x

Aust NZ J Obst Gynaeco

1991

DOI: 10.1111/j.1479-828x.1991.tb02763.x

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The Use of 16.16‐dimethyl‐PGEl‐ A‐methyl ester (Cervagem) Vaginal Pessaries for Cervical Dilatation Prior to Evacuation for Second Trimester Termination

Mark J. Bennett

S. D. .Horrowitz

Debbie M. Wass

Abstract: The results of a study of 101 consecutive second trimester terminations by Dilatation and Evacuation (D & E) under ultrasound control is presented. All had a Cervagem pessary inserted into the vagina prior to the procedure. The PGE1 analogue was assessed as 'effective' in 97% of patients. Concomitant ultrasound resulted in no patient leaving the operating table with retained products. The high efficacy of the single pessary associated with a low incidence of side-effects makes this combination the method of ch… Show more

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Cited by 4 publications

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Mid-trimester termination of pregnancy by dilatation and evacuation

Panoskaltsis

2001

Journal of Obstetrics and Gynaecology

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The object of this study was to evaluate the feasibility and safety of Dilatation and Evacuation (D&E) as a method of termination of pregnancy in the second trimester. We conducted a retrospective analysis of 61 cases. The mean age of women was 25.6 years (range 1545) and the majority of terminations were performed for social reasons. Twelve women (20%) had at least one previous termination of pregnancy. The median gestational age was 16 weeks (range 1322). Except for three multiparous women, they all had Cervagem vaginal pessaries preoperatively and the mean operative time was 26.6 minutes. Most of the operations were performed under ultrasound guidance, but there was no increased risk of complications in the rest of the group. One multiparous woman suffered uterine perforation and severe haemorrhage, for which she underwent hysterectomy. One in four women tested positive for chlamydia infection. Evacuation of retained products of conception (ERPC) was required in four cases. No postoperative analgesia was required in 43% of women and most of the rest required only mild non-opiate analgesia. Except for two women, all were discharged from the hospital either on the same or the day after the operation. This retrospective study shows that surgical evacuation in the second trimester of pregnancy is a quick and well tolerated method of termination, although there is a risk of perforation and hysterectomy.

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Mid-trimester termination of pregnancy by dilatation and evacuation

Panoskaltsis

2001

Journal of Obstetrics and Gynaecology

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Predilatation of the Cervix Before Suction Curettage for Therapeutic Abortion in Early Pregnancy

Edwards

Aitken

Begg

et al. 1994

Aust NZ J Obst Gynaeco

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Prolonged Induction to Delivery Time in Termination of Pregnancy Using 16,16‐dimethyl‐PGErmethyl ester (gemeprost) for Fetuses with a Neural Tube Defect or Hydrocephalus

Nesbitt

Giles

1996

Aust NZ J Obst Gynaeco

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Summary: A retrospective study is reported comparing the induction to delivery interval using gemeprost for termination of pregnancy, in the second trimester, in 3 groups of patients. It was observed that the mean induction to delivery interval was significantly longer in 75 pregnancies where there was a fetus with a neural tube defect and or hydrocephalus (31.7 hours) compared with 88 pregnancies with other fetal abnormalities (19.7 hours) and 84 pregnancies where there was an intrauterine death (113 hours). There was also an increase in the requirements for further intervention to obtain delivery in the group with a neural tube defect or hydrocephalus (n=33) compared with where there was an intrauterine fetal death (n=4) and other abnormality (n=14). We believe these results should be considered when counselling patients who have requested termination of pregnancy for fetal abnormalities.

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The Use of 16.16‐dimethyl‐PGEl‐ A‐methyl ester (Cervagem) Vaginal Pessaries for Cervical Dilatation Prior to Evacuation for Second Trimester Termination

Cited by 4 publications

References 8 publications

Mid-trimester termination of pregnancy by dilatation and evacuation

Mid-trimester termination of pregnancy by dilatation and evacuation

Predilatation of the Cervix Before Suction Curettage for Therapeutic Abortion in Early Pregnancy

Prolonged Induction to Delivery Time in Termination of Pregnancy Using 16,16‐dimethyl‐PGErmethyl ester (gemeprost) for Fetuses with a Neural Tube Defect or Hydrocephalus

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