AThe present study aims to discuss corruption, its causes, and its persistence using the research agenda proposed by Bo Rothstein. As a rule, studies and theories have analysed corruption using structural variables like the economy, social development, and democracy, among others. Nevertheless, little has been explained about the role of other-non-structural-variables in generating and sustaining corruption, such as interpersonal/institutional trust and social dilemmas. Therefore, this study will use data obtained from the Vanderbilt University project Americas Barometer in 2014 to analyse the case of Ecuador. The objective of this paper is twofold: first, to contrast the claims of major theories of structural causes of corruption with what is observed in Ecuador, and second, to use Rothstein's framework to assess the links between trust, social dilemmas, and corruption in the selected case study. From this analysis, we can assert that the hypotheses constructed by Rothstein are confirmed in the case of Ecuador. On the one hand, there seems to be a positive correlation between vertical and horizontal trust in the country. On the other hand, looking at the fitted models, it is also possible to claim that there is a negative association between interpersonal trust and the perception and persistence of corruption in Ecuador.