The unity of approaches to preventing coronary heart disease and cerebrovascular diseases

Kim, I. V.; Bochkareva, E. V.; Варакин, Ю.Я.

doi:10.17116/profmed201518624-33

Profil. med.

2015

DOI: 10.17116/profmed201518624-33

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The unity of approaches to preventing coronary heart disease and cerebrovascular diseases

I. V. Kim¹,

E. V. Bochkareva²,

Ю.Я. Варакин³

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Cited by 3 publications

References 59 publications

(46 reference statements)

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Theoretical background of hypoxytherapy

Ignatenko

2023

Russian Medicine

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The review discusses the structure and physiology of the oxygen supply functional system, its self-regulatory potential and the role in maintaining the bodys optimal metabolic homeostasis level of blood gases. Up-to-date data on the functioning of peripheral (arterial) and central (medullary) chemoreceptors, molecular mechanisms of the oxygen and carbon dioxide content and pH perception, as well as on their association with afferent nerve endings are presented. The paths and centers of the chemosensory reflex in various departments of the brain, effector elements, and reverse afferentation mechanisms are shown. Response patterns to exogenous and endogenous hypoxic stimuli from the side of the oxygen supply systems various elements are described. The role of intracellular HIF-dependent and HIF-independent pathways in the adaptive reactions implementation for maintaining the optimal intracellular metabolism is demonstrated. Cell mechanisms claiming to play the role of adaptive ones in hypoxia/reoxygenation under the conditions of interval normobaric hypoxic therapy are discussed. The review of current concepts and analysis of research results on the physiology of the oxygen supply functional system, its structural and functional status, and its molecular regulation under the exogenous hypoxia conditions will draw attention to the expediency of further randomised clinical trials of interval normobaric hypoxytherapy as a rehabilitation method for patients with chronic cardiovascular diseases.

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Theoretical background of hypoxytherapy

Ignatenko

2023

Russian Medicine

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On the Quality of Medical Examination: Diagnostic Significance of the Survey Method for Detecting the Probability of Cardio-Cerebral Symptoms

Калинина¹,

Antonov²,

Горный³

et al. 2020

Racionalʹnaâ farmakoterapiâ v kardiologii

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Cerebral dysfunction in patients with acute myocardial infarction

Muradyan,

Kuzmina,

Gvindzhiliya

et al. 2023

Transplantologiâ (Mosk.)

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Background. The article discusses the features of one of the complications of acute myocardial infarction – cerebral dysfunction, which negatively affects the quality of life of patients, worsens the disease prognosis, increases the hospital length of stay and the risk of death. The presence of cerebral disorders in patients with acute myocardial infarction causes difficulties in the choice of therapeutic tactics, including the decision on myocardial revascularization. The identification of predictive factors for cerebral deficiency in acute myocardial infarction and the development of an algorithm for the management of such patients is an urgent task of today medicine.Aim. To study the features of cerebral dysfunction in patients with myocardial infarction according to contemporary Russian and foreign literature sources. To create an algorithm for the diagnosis and treatment of cerebral dysfunction in patients with acute myocardial infarction.Material and methods. Patients with acute myocardial infarction who developed cerebral dysfunction in the acute period of the disease were examined.Conclusion. Timely diagnosis, antiplatelet therapy, emergency reperfusion therapy in the acute period of myocardial infarction, as well as preventive measures reduce the development of cerebral complications, improve the results of treatment of patients with myocardial infarction, reduce the number of inpatient treatment days, as well as improve the long term prognosis.

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The unity of approaches to preventing coronary heart disease and cerebrovascular diseases

Cited by 3 publications

References 59 publications

Theoretical background of hypoxytherapy

Theoretical background of hypoxytherapy

On the Quality of Medical Examination: Diagnostic Significance of the Survey Method for Detecting the Probability of Cardio-Cerebral Symptoms

Cerebral dysfunction in patients with acute myocardial infarction

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