The unique nanostructure of shellac films

Bar, Hedva; Bianco‐Peled, Havazelet

doi:10.1016/j.porgcoat.2021.106328

Cited by 16 publications

(9 citation statements)

References 52 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…3 The compositions of the cyclic compounds of shellac are complex, and their structures are related to the side reaction during the hydrolysis of the shellac resin. 4,5 These results indicate that the numbers of chains in shellac resin are low while their amounts are high and concentrated, whereas cyclic compounds are larger in size but more dispersed. Therefore, aleuritic acid represents a feasible option for the preparation of antibodies.…”

Section: Introductionmentioning

confidence: 94%

A new method for shellac binder detection in ancient building mortars

Zhang

Zhu

2022

New J. Chem.

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 94%

A new method for shellac binder detection in ancient building mortars

Zhang

Zhu

2022

New J. Chem.

View full text Add to dashboard Cite

show abstract

“…This phenomenon, referred to as aging, also restricts the application of shellac coatings. Generally, the shellac polymerization reaction produces alcohol-insoluble solids, which can be used to characterize the degree of polymerization of shellac. , Limmatvapirat et al . and Bar et al .…”

Section: Shellac-based Delivery Systemsmentioning

confidence: 99%

“…Generally, the shellac polymerization reaction produces alcohol-insoluble solids, which can be used to characterize the degree of polymerization of shellac. , Limmatvapirat et al . and Bar et al . reported that the solid content accounts for more than 60% of fresh shellac film weight after being stored at 40 °C and 75% relative humidity for 90 days.…”

Section: Shellac-based Delivery Systemsmentioning

confidence: 99%

“…One of the barriers is the industrial production of shellac-based film formulations, which prompts innovation in the existing production technology . Another barrier is the polymerization of shellac, which results in the weaker stability of shellac-based films . Generally, for film formulations, the film must be sufficiently stable to ensure the activity of the active substance during storage and use.…”

Section: Shellac-based Delivery Systemsmentioning

confidence: 99%

“…As an enteric coating, the enteric properties of shellac endow it with a natural advantage, which is illustrated by the aforementioned studies; however, the instability caused by its polymerization remains an issue that needs to be addressed for its future development . At present, shellac is mainly used as an enteric coating for the delivery of drugs.…”

Section: Shellac-based Delivery Systemsmentioning

confidence: 99%

See 2 more Smart Citations

Multiscale Shellac-Based Delivery Systems: From Macro- to Nanoscale

Yuan

Dong

et al. 2021

ACS Nano

View full text Add to dashboard Cite

Delivery systems play a crucial role in enhancing the activity of active substances; however, they require complex processing techniques and raw material design to achieve the desired properties. In this regard, raw materials that can be easily processed for different delivery systems are garnering attention. Among these raw materials, shellac, which is the only pharmaceutically used resin of animal origin, has been widely used in the development of various delivery systems owing to its pH responsiveness, biocompatibility, and degradability. Notably, shellac performs better on encapsulating hydrophobic active substances than other natural polymers, such as polysaccharides and proteins. In addition, specially designed shellac-based delivery systems can also be used for the codelivery of hydrophilic and hydrophobic active substances. Shellac is most widely used for oral administration, as shellac-based delivery systems can form a compact structure through hydrophobic interaction, protecting transported active substances from the harsh environment of the stomach to achieve targeted delivery in the small intestine or colon. In this review, the advantages of shellac in delivery systems are discussed in detail. Multiscale shellac-based delivery systems from the macroscale to nanoscale are comprehensively introduced, including matrix tablets, films, enteric coatings, hydrogels, microcapsules, microparticles (beads/spheres), nanoparticles, and nanofibers. Furthermore, the hotspots, deficiencies, and future perspectives of shellac-based delivery system development are also analyzed. We hoped this review will increase the understanding of shellac-based delivery systems and inspire their further development.

show abstract