The TwinEBIS setup: Machine description

Breitenfeldt, M.; Mertzig, Robert; Pitters, Johanna; Shornikov, A.; Wenander, F.

doi:10.1016/j.nima.2016.12.037

Cited by 12 publications

(4 citation statements)

References 24 publications

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“…This LINAC concept consists of 5 substructures. A TwinEBIS source [14,15] delivers 12 C 6+ -ions. The ions are initially accelerated and transferred to a subsequent RFQ accelerator by the Low Energy Beam Transport (LEBT).…”

Section: Hadron Minibeam Irradiation Facility Conceptmentioning

confidence: 99%

A carbon minibeam irradiation facility concept

Mayerhofer

Bencini

Sammer

et al. 2023

J. Phys.: Conf. Ser.

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In minibeam therapy, the sparing of deep-seated normal tissue is limited by transverse beam spread caused by small-angle scattering. Contrary to proton minibeams, helium or carbon minibeams experience less deflection, which potentially reduces side effects. To verify this potential, an irradiation facility for preclinical and clinical studies is needed. This manuscript presents a concept for a carbon minibeam irradiation facility based on a LINAC design for conventional carbon therapy. A quadrupole triplet focuses the LINAC beam to submillimeter minibeams. A scanning and a dosimetry unit are provided to move the minibeam over the target and monitor the applied dose. The beamline was optimized by TRAVEL simulations. The interaction between beam and these components and the resulting beam parameters at the focal plane is evaluated by TOPAS simulations. A transverse beamwidth of < 100 μm (sigma) and a peak-to-valley (energy) dose ratio of > 1000 results for carbon energies of 100 MeV/u and 430 MeV/u (∼ 3 cm and 30 cm range in water) whereby the average beam current is ∼ 30 nA. Therefore, the presented irradiation facility exceeds the requirements for hadron minibeam therapy.

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Section: Hadron Minibeam Irradiation Facility Conceptmentioning

confidence: 99%

A carbon minibeam irradiation facility concept

Mayerhofer

Bencini

Sammer

et al. 2023

J. Phys.: Conf. Ser.

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“…The gun underwent several design modifications related to the optics simulations and mechanical structure and in the summer of 2016 the project was concluded with the electron gun delivering a current of 3.14 A [33]. Based on the lessons learned, a project to retrofit a doublecompression gun into a test bench replica of the REX charge breeder was started at CERN [34,35]. As of December 2016, all of the gun components have been manufactured and are being assembled.…”

Section: Hrs Separator Magnetmentioning

confidence: 99%

The ISOLDE facility

Catherall¹,

Andreazza²,

Breitenfeldt³

et al. 2017

J. Phys. G: Nucl. Part. Phys.

180

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The ISOLDE facility has undergone numerous changes over the last 17 years driven by both the physics and technical community with a common goal to improve on beam variety, beam quality and safety. Improvements have been made in civil engineering and operational equipment while continuing developments aim to ensure operations following a potential increase in primary beam intensity and energy. This paper outlines the principal technical changes incurred at ISOLDE by building on a similar publication of the facility upgrades by Kugler (2000 Hyperfine Interact. 129 23–42). It also provides an insight into future perspectives through a brief summary issues addressed in the HIE-ISOLDE design study Catherall et al (2013 Nucl. Instrum. Methods Phys. Res. B 317 204–207).

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“…The rationale of such a machine is to improve the aspect ratio of its footprint, studying a solution that could better fit into a hospital facility without affecting the treatment beam properties. In the low energy section of the machine, fully stripped carbon ions ( 12 C 6+ ) are produced by the ion source (TwinEBIS, operating at CERN [5]), transported in the Low Energy Beam Transport (LEBT) [6] and matched to the Radio Frequency Quadrupole (RFQ), which represents the first rf accelerating structure. The RFQ has the critical role of shaping the beam in both the transverse and the longitudinal plane and prepare it for the injection in the following accelerating structures.…”

Section: Introductionmentioning

confidence: 99%

750 MHz radio frequency quadrupole with trapezoidal vanes for carbon ion therapy

Bencini,

Pommerenke,

Grudiev

et al. 2020

Preprint

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High-frequency linear accelerators are very suitable for carbon ion therapy, thanks to the reduced operational costs and the high beam quality with respect to synchrotrons, which are presently the only available technology for this application. In the framework of the development of a new linac for carbon ion therapy, this article describes the design of a compact 750 MHz Radio Frequency Quadrupole (RFQ) with trapezoidal vanes. A new semi-analytic approach to design the trapezoidalvane RFQ is introduced together with the relevant beam dynamics properties. The RFQ is split into two decoupled rf cavities, both of which make use of a novel dipole detuning technique by means of length adjustment. The splitting is described both from the rf and the beam dynamics point of view. The paper concludes with the rf design of the full structure, including maximum surface field and thermal studies.

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The TwinEBIS setup: Machine description

Cited by 12 publications

References 24 publications

A carbon minibeam irradiation facility concept

A carbon minibeam irradiation facility concept

The ISOLDE facility

750 MHz radio frequency quadrupole with trapezoidal vanes for carbon ion therapy

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