The turbot macrophage mannose receptor: Phylogenetic analysis, functional characterization and changes in gene expression during vaccination and infection with Philasterides dicentrarchi
Abstract:The mannose receptor is a carbohydrate-binding receptor expressed in some populations of macrophages and dendritic cells and non vascular endothelium in mammals. It has been described as a transmembrane protein with three types of extracellular domains: a cysteine rich domain, a fibronectin type II repeat and eight carbohydrate recognition domains. This highly effective endocytic receptor is involved in capture and clearance of pathogens, capture of foreign antigens for presentation to MHC-II compartments, and… Show more
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