The Truth Behind Subchondral Cysts in Osteoarthritis of the Knee

Audrey, Han Xinyun; Razak, Hamid Rahmatullah Bin Abd; Andrew, Tan Hwee Chye

doi:10.2174/1874325001408010007

Cited by 57 publications

(40 citation statements)

References 17 publications

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“…The discrepancy in gender difference and age correlation between STB and DTB may be due to the distinct roles of these two structures in maintaining joint homeostasis. Consistent with previous studies [52][53][54][55][56], our study also showed a high frequency of SBC in late-stage OA. However, the frequency of cysts in DTB was much lower compared to that in STB.…”

Section: Discussionsupporting

confidence: 93%

Influence of age and gender on microarchitecture and bone remodeling in subchondral bone of the osteoarthritic femoral head

Zheng

Landao-Bassonga

et al. 2015

Bone

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Section: Discussionsupporting

confidence: 93%

Influence of age and gender on microarchitecture and bone remodeling in subchondral bone of the osteoarthritic femoral head

Zheng

Landao-Bassonga

et al. 2015

Bone

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“…Then, the bone starts the healing process by resorbing the necrotic areas, which provide a passage for the synovial fluid to intrude into the bone, resulting in subchondral cyst formation. 33 …”

Section: Discussionmentioning

confidence: 99%

Osseous changes in the temporomandibular joint in rheumatoid arthritis: A cone-beam computed tomography study

et al. 2018

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PurposeTo evaluate osseous changes of temporomandibular joint (TMJ) in patients with rheumatoid arthritis (RA) using cone-beam computed tomography (CBCT) and to correlate the imaging findings with the severity of TMJ dysfunction, clinical findings, and laboratory findings.Materials and MethodsThis study consisted of 28 subjects, including 14 RA patients and 14 controls, who were scheduled to undergo CBCT imaging for the diagnosis of a complaint not related to or affecting the TMJ. The Fonseca's questionnaire was used to assess the severity of TMJ dysfunction. Rheumatoid factor (RF) and the erythrocyte sedimentation rate (ESR) were assessed in the RA patients. CBCT was then performed in all subjects and osseous TMJ abnormalities were assessed.ResultsAccording to the Fonseca's questionnaire, 14.3% of the patients had no TMJ dysfunction, while 50%, 21.4%, and 14.3% had mild, moderate, and severe dysfunction, respectively. RF was positive in 64.3% of patients, and the ESR level was high in 100%. Imaging findings revealed a statistically significantly higher prevalence of erosion (85.7%), flattening (89.3%), osteophyte formation (32.1%), subchondral cyst (32.1%), sclerosis (64.3%), and condylar irregularities (28.6%) in the RA patients than in the controls. No correlations were found between CBCT findings and the clinical findings, the severity of TMJ dysfunction, disease duration, or laboratory results.ConclusionRA patients might show extensive osseous abnormalities with no/mild clinical signs or symptoms of TMJ dysfunction that necessitate TMJ imaging for these patients. CBCT is a valuable and efficient modality that can assess osseous TMJ changes in RA patients.

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“…They can present in conditions such as osteoarthritis, rheumatoid arthritis, calcium pyrophosphate deposition disease, and osteonecrosis, but still the physiopathologic process is unclear. 1 Two theories have been postulated: the synovial intrusion theory and the bony contusion theory. The first suggests a connection between the articular and cystic cavities that allows the synovium to enter and enlarge the defect.…”

mentioning

confidence: 99%

“…The necrotic area is further remodeled with bone fragments phagocytosed by osteoclasts, creating a subchondral cystic cavity. 1 , 2 , 3 …”

mentioning

confidence: 99%

Intraosseous Bioplasty for a Chondral Cyst in the Lateral Tibial Plateau

Elena¹,

Woodall²,

Lee³

et al. 2018

Arthroscopy Techniques

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Subchondral lesions are the result of osseous modifications seen in a different array of pathologies such as osteoarthritis, rheumatoid arthritis, calcium pyrophosphate deposition, and osteonecrosis. The physiopathologic changes in all of the aforementioned pathologies are not clear yet. What is clear is that the development of a cystic change in the subchondral bone can cause pain and can lead to modification of the activity of daily life. To provide relief and treatment for such a condition, there are different options with joint replacement as last resort when the cyst develops in communication with the joint; if the cyst is not in communication with the joint, it is possible to perform a bioplasty as we present in this technical report. It is crucial to assess the bone continuity, especially when traumas are reported in the patient history. In our case, the tibial plateau did not have signs of collapse. The technique here presented is a minimally invasive technique that can be reproduced for focal and localized subchondral cysts.

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The Truth Behind Subchondral Cysts in Osteoarthritis of the Knee

Cited by 57 publications

References 17 publications

Influence of age and gender on microarchitecture and bone remodeling in subchondral bone of the osteoarthritic femoral head

Influence of age and gender on microarchitecture and bone remodeling in subchondral bone of the osteoarthritic femoral head

Osseous changes in the temporomandibular joint in rheumatoid arthritis: A cone-beam computed tomography study

Intraosseous Bioplasty for a Chondral Cyst in the Lateral Tibial Plateau

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