The treatment of tumours of the upper jaw

Lederman, M.; Busby, Elizabeth; Mould, Richard F.

doi:10.1259/0007-1285-42-500-561

Cited by 32 publications

(9 citation statements)

References 1 publication

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“…The 5-year survival of 45% in this series seems to be at the same level. The histolopathologic pattern is similar to findings in other series (4,5 ) and the varied picture contributes to the complexity of deciding the best treatment modality for cancer of the upper jaw. The topographic distribution does not resemble two large series from the 1950s and 1960s, as cancer of the nasal cavity are almost 50% in the present series, compared with 20-30% in the older series (4,5).…”

Section: Discussionsupporting

confidence: 75%

“…The histolopathologic pattern is similar to findings in other series (4,5 ) and the varied picture contributes to the complexity of deciding the best treatment modality for cancer of the upper jaw. The topographic distribution does not resemble two large series from the 1950s and 1960s, as cancer of the nasal cavity are almost 50% in the present series, compared with 20-30% in the older series (4,5). In general, the distribution of the two subsites has changed from a predominance of maxillary sinus cancers during the 1940s and 1950s to a predominance of nasal cavity cancers in the 1970s and 1980s (6).…”

Section: Discussionsupporting

confidence: 75%

See 1 more Smart Citation

Cancer of the Nasal Cavity and Paranasal Sinuses:Prognosis and Outcome of Treatment

et al. 1997

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Section: Discussionsupporting

confidence: 75%

Section: Discussionsupporting

confidence: 75%

Cancer of the Nasal Cavity and Paranasal Sinuses:Prognosis and Outcome of Treatment

et al. 1997

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“…In accordance with other studies (2, 3) a good correlation between tumour staging and death ratio was found, especially in the systems proposed by the American Joint Committee (1) and LEDERMAN (7). The largest diameter of the tumour of the destruction as seen on the film showed, however, exactly the same correlation.…”

Section: Discussionsupporting

confidence: 90%

“…There is no generally accepted method for clinical staging of tumours in the paranasal sinuses and nasal cavity. Several systems have been proposed especially for maxillary sinus carcinomas (4,6,7), and another system has been based on the definition of T category of the maxillary antrum by the American Joint Committee (1).…”

Section: Methodsmentioning

confidence: 99%

Malignant Tumours of the Paranasal Sinuses and Nasal Cavity a Series of 180 Patients

Gadeberg

Hjelm-Hansen

Søgaard

et al. 1984

Acta Radiologica: Oncology

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“…All calculations were performed using Microsoft Excel. Also, because the proportions cured C SLN , C TCR and C ACC in the models are expressed as fractions rather than as percentage rates the convention of using fractions is continued for overall survival (OSF) and cancer-specific survival (CSF) (Lederman 1964, 1967, 1971, Lederman and Mould 1968, Lederman et al 1969. The same data resource has previously been used to study lognormal distributions of symptom duration times (Mould et al 1987) and for Phase 1 SLN model validation for subsites of head and neck cancer (Mould et al 1976).…”

Section: Cancer Risk and Cure Modelsmentioning

confidence: 99%

Field configuration in a resonator with a diffuse reflector

Belonuchkin¹,

Kozel²,

Lokshin³

1979

Sov. J. Quantum Electron.

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Three parametric statistical models have been fully validated for cancer of the larynx for the prediction of long-term 15, 20 and 25 year cancer-specific survival fractions when short-term follow-up data was available for just 1-2 years after the end of treatment of the last patient. In all groups of cases the treatment period was only 5 years. Three disease stage groups were studied, T1N0, T2N0 and T3N0. The models are the Standard Lognormal (SLN) first proposed by Boag (1949 J. R. Stat. Soc. Series B 11 15-53) but only ever fully validated for cancer of the cervix, Mould and Boag (1975 Br. J. Cancer 32 529-50), and two new models which have been termed Tobacco Cancer Risk (TCR) and Absolute Cancer Cure (ACC). In each, the frequency distribution of survival times of defined groups of cancer deaths is lognormally distributed: larynx only (SLN), larynx and lung (TCR) and all cancers (ACC). All models each have three unknown parameters but it was possible to estimate a value for the lognormal parameter S a priori. By reduction to two unknown parameters the model stability has been improved. The material used to validate the methodology consisted of case histories of 965 patients, all treated during the period 1944-1968 by Dr Manuel Lederman of the Royal Marsden Hospital, London, with follow-up to 1988. This provided a follow-up range of 20-44 years and enabled predicted long-term survival fractions to be compared with the actual survival fractions, calculated by the Kaplan and Meier (1958 J. Am. Stat. Assoc. 53 457-82) method. The TCR and ACC models are better than the SLN model and for a maximum short-term follow-up of 6 years, the 20 and 25 year survival fractions could be predicted. Therefore the numbers of follow-up years saved are respectively 14 years and 19 years. Clinical trial 5 Deceased.

show abstract

The treatment of tumours of the upper jaw

Cited by 32 publications

References 1 publication

Cancer of the Nasal Cavity and Paranasal Sinuses:Prognosis and Outcome of Treatment

Cancer of the Nasal Cavity and Paranasal Sinuses:Prognosis and Outcome of Treatment

Malignant Tumours of the Paranasal Sinuses and Nasal Cavity a Series of 180 Patients

Field configuration in a resonator with a diffuse reflector

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