Eighty-one cases of uterine rupture in Conakry/Guinea are analyzed. With an incidence of 0.84%, i.e. 1 per 119 deliveries, uterine rupture is still a common problem in this region. In this analysis fetal mortality was found to be 75.3% and maternal mortality 20.9%. Mortality rates were statistically higher after hysterectomy than after repair. Other etiologic factors were extreme multiparity and an inadequate transfer system to the obstetric centers. A reduction of uterine rupture rates can be achieved by prevention of extreme multiparity (more than 4 deliveries) and of home deliveries and decentralization of obstetric services into peripheral units and villages.