The Treatment of Rectal Prolapse in Children with Phenol in Almond Oil Injection

Sasaki, Yoshitaka; Iwai, Naoharu; Kimura, Osamu; Hibi, Masahito

doi:10.1055/s-2004-821151

Cited by 19 publications

(17 citation statements)

References 1 publication

(2 reference statements)

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“…The publications about the value of the use of phenol as sclerosing agent for PR have been mixed. One report indicated 89% cure rates after one or two injections . This study reported 100% cure rates after three injections and documented no complications.…”

Section: Discussionmentioning

confidence: 63%

Death Following Injection Sclerotherapy Due to Phenol Toxicity

Philip

Marraffa²

2012

Journal of Forensic Sciences

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Prolapse rectum (PR) or protrusion of the rectum beyond the anus occurs frequently in populations at both extremes of age. In the pediatric population, in developed countries, the commonest cause for PR is thought to be cystic fibrosis (CF). Treatment options for CF include conservative management, surgical resection and fixation, suturing, and injection sclerotherapy (IS). The last is considered an attractive treatment option because it is minimally invasive. In this case report, the authors present the details about a 2-year-old female child, with PR and CF, who died after IS, using phenol as the sclerotherapeutic agent. Autopsy findings and toxicology tests performed to establish phenol toxicity are documented. The available literature is reviewed. This case report underscores the risks of using phenol for IS and emphasizes the point that the procedure is not innocuous and an adverse outcome including fatality is a possibility.

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Section: Discussionmentioning

confidence: 63%

Death Following Injection Sclerotherapy Due to Phenol Toxicity

Philip

Marraffa²

2012

Journal of Forensic Sciences

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“…Some of the substances used include alcohol, phenol and deflux 5. Sclerotherapy using phenol-in-almond-oil injection has been reported to yield favourable results 7. Although safe, simple and effective, phenol injection carries the risk of several possible complications including bleeding, perirectal inflammation, urinary retention, ischiorectal abscess and necrosis of rectal mucosa.…”

Section: Discussionmentioning

confidence: 99%

Successful treatment of recurrent rectal prolapse using three Thiersch sutures in children

2015

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Many techniques are described to manage recurrent rectal prolapse in children, including repeated Thiersch stitch, phenol injections, Delorme and Altemeier procedures, and rectopexy. We describe a case of successful treatment of rectal prolapse by placing three Thiersch sutures circumferentially along the anal canal--a simple and novel modification of a well-known procedure. An 8-year-old boy with full-thickness rectal prolapse was treated with laxatives to no avail. He was subsequently treated with phenol-in-almond-oil injection and insertion of a 1/0PDS Thiersch suture. The effects were temporary with recurrence 3 months later. A further phenol-in-almond-oil injection was given and a 1/0PDS Thiersch suture placed, and the patient was discharged on laxatives. Recurrence occurred again at 3 months. This was treated with three circumferential Thiersch sutures along the anal canal--one Prolene 2/0 and two 1/0PDS. There has been no recurrence at follow-up. Placement of three sequential Thiersch sutures along the rectum is effective in treating recurrent rectal prolapse and a good alternative to major rectopexy.

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“…Submucosal injection with a sclerosing agent is known as the simplest, most minimally invasive, and most highly effective approach to providing the anatomical integrity required to maintaining or restoring attachment of the rectal mucosa, and it is widely accepted as a treatment modality [4]. Many agents have been used as sclerosing agents for the treatment of RP, including 15% saline, 30% saline, 70%-98% ethyl alcohol, 50% dextrose, 5% PAO, and cow's milk [3,[5][6][7][8][9][10][11][12][13]18].…”

Section: Discussionmentioning

confidence: 99%

“…Sclerotherapy for managing RP is expected to induce intense fibrosis resulting from histopathological changes between the rectal mucosa and submucosal tissue to prevent RP [9,[17][18][19]. Thus, it is not a completely safe procedure.…”

Section: Discussionmentioning

confidence: 99%

“…Sasaki et al [18] and Soomro and Solangi [5] preferred to use 5% PAO as the sclerosing agent and reported no complications with 67% and 100% success rates, respectively, following one submucosal injection of 5% PAO for the treatment of RP. Experimental studies have shown that fibrosis can be stimulated by inducing an inflammatory reaction using different types of synthetic prosthesis [22,23].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Comparative effects of different sclerosing agents used to treat rectal prolapse: An experimental study in rats

Ezer

Kayaselçuk

Oğuzkurt

et al. 2013

Journal of Pediatric Surgery

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The Treatment of Rectal Prolapse in Children with Phenol in Almond Oil Injection

Abstract: PAO injection sclerotherapy is simple and should be recommended as a first method of treatment for rectal prolapse in children. PAO as a sclerosing agent did not cause any complications.

Cited by 19 publications

References 1 publication

Death Following Injection Sclerotherapy Due to Phenol Toxicity

Death Following Injection Sclerotherapy Due to Phenol Toxicity

Successful treatment of recurrent rectal prolapse using three Thiersch sutures in children

Comparative effects of different sclerosing agents used to treat rectal prolapse: An experimental study in rats

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