The Treatment of Osteoporotic–Posttraumatic Vertebral Collapse Using the Kaneda Device and a Bioactive Ceramic Vertebral Prosthesis

Kaneda, Kiyoshi; Asano, Satoshi; Hashimoto, Tomoyuki; Satoh, Shun; Fujiya, Masanori

doi:10.1097/00007632-199208001-00015

Cited by 202 publications

(135 citation statements)

References 0 publications

Supporting

Mentioning

127

Contrasting

Unclassified

Order By: Relevance

“…In the present study, marked angular instability of the affected vertebral body significantly contributed to severity of back pain. The presence of an intravertebral cleft had been reported to be a risk factor for progressive vertebral collapse inducing neurological deficits [15,17]. A few previous studies investigated the relationship between neurological deficits and radiological findings.…”

Section: Discussionmentioning

confidence: 99%

Factors affecting neurological deficits and intractable back pain in patients with insufficient bone union following osteoporotic vertebral fracture

et al. 2009

View full text Add to dashboard Cite

The purpose of this study was to examine factors affecting the severity of neurological deficits and intractable back pain in patients with insufficient bone union following osteoporotic vertebral fracture (OVF). Reports of insufficient union following OVF have recently increased. Patients with this lesion have various degrees of neurological deficits and back pain. However, the factors contributing to the severity of these are still unknown. A total of 45 patients with insufficient union following OVF were included in this study. Insufficient union was diagnosed based on the findings of vertebral cleft on plain radiography or CT, as well as fluid collection indicating high-intensity change on T2-weighted MRI. Multivariate logistic regression analysis was performed to determine the factors contributing to the severity of neurological deficits and back pain in the patients. Age, sex, level of fracture, duration after onset of symptoms, degree of local kyphosis, degree of angular instability, ratio of occupation by bony fragments, presence or absence of protrusion of flavum, and presence or absence of ossification of the anterior longitudinal ligament (OALL) in the adjacent level were used as explanatory variables, while severity of neurological deficits and back pain were response variables. On multivariate analysis, factors significantly affecting the severity of neurological deficits were angular instability of more than 15°[adjusted odds ratio (OR), 9.24 (95% confidence interval, CI 1.49-57.2); P \ 0.05] and ratio of occupation by bony fragments in the spinal canal of more than 42% [adjusted OR 9.23 (95%CI 1.15-74.1); P \ 0.05]. The factor significantly affecting the severity of back pain was angular instability of more than 15°[ adjusted OR 14.9 (95%CI 2.11-105); P \ 0.01]. On the other hand, presence of OALL in the adjacent level reduced degree of back pain [adjusted OR 0.14 (95%CI 0.03-0.76); P \ 0.05]. In this study, pronounced angular instability and marked posterior protrusion of bony fragments in the canal were factors affecting neurological deficits. In addition, marked angular instability was a factor affecting back pain. These findings are useful in determining treatment options for patients with insufficient union following OVF.

show abstract

Section: Discussionmentioning

confidence: 99%

Factors affecting neurological deficits and intractable back pain in patients with insufficient bone union following osteoporotic vertebral fracture

et al. 2009

View full text Add to dashboard Cite

show abstract

“…To date, controversies still prevail regarding terminology, pathogenesis, and treatment of this condition. Accordingly, a variety of surgical procedures have been reported, including osteosynthesis [5], decompression and fusion surgeries by anterior [6,7], posterior [7][8][9], and anteroposterior [10] approaches, percutaneous vertebroplasty (PVP) [11][12][13], and percutaneous kyphoplasty [14]. Whereas osteosynthesis and fusion surgeries aim at solid bone union for stabilization of the affected vertebra, union status following PVP or percutaneous kyphoplasty has not yet been addressed.…”

Section: Introductionmentioning

confidence: 99%

Conversion to hypertrophic vertebral pseudarthrosis following percutaneous vertebroplasty

et al. 2010

View full text Add to dashboard Cite

To determine the role of percutaneous vertebroplasty (PVP) in bone formation and the union of vertebral pseudarthrosis, we analyzed 14 patients with an average follow-up duration of 21 months. Evaluation methods included back pain (visual analog scale: VAS), wedge angle, dynamic mobility, radiographic remodeling including callus and spur formation, and union status. The Student's t test was used for statistical analysis and a probability of less than 0.05 was determined as a significant difference. Back pain improved in all 14 patients with a VAS score of 57.8 ± 23.5 mm (average ± standard deviation) preoperatively and 14.7 ± 16.4 mm at the final follow-up (P \ 0.001). The wedge angle decreased from 21.6°± 8.3°(average ± standard deviation) preoperatively to 13.2°± 6.9°at the final follow-up (P \ 0.001). Callus formation was seen in four patients. Bony spurs were seen in the affected vertebra in preoperative radiographs in all patients, and were further developed to a solidified form during follow up after PVP. Dynamic mobility of the affected vertebrae was 6.9 ± 2.9 mm preoperatively, which decreased to 1.1°± 0.7°at the final follow-up (P \ 0.001). Notably, all patients showed the dynamic vertebral mobility of 2 mm or less. Nevertheless, only two patients exhibited the dynamic vertebral mobility of 0 mm at the final follow-up, which is referred to as bone union. These findings indicate that PVP serves as a mechanical stabilizer for vertebral pseudarthrosis, which leads to immediate pain relief and segmental bony responses.

show abstract

“…Augmentation to clinical study using sintered bone Bioactive materials that possess excellent strength in themselves, such as titanium cage and Apatite and Wollastonite coating glass ceramics (A-W glass ceramics), have been applied clinically to reconstructive spinal stabilization [1,3,6,10]. However, there are doubts about whether spinal reconstruction requires biomaterials that S186 Fig.…”

Section: Resultsmentioning

confidence: 99%

The use of sintered bone in spinal surgery

Minamide

Tamaki

Yoshida

et al. 2001

European Spine Journal

View full text Add to dashboard Cite

The Treatment of Osteoporotic–Posttraumatic Vertebral Collapse Using the Kaneda Device and a Bioactive Ceramic Vertebral Prosthesis

Cited by 202 publications

References 0 publications

Factors affecting neurological deficits and intractable back pain in patients with insufficient bone union following osteoporotic vertebral fracture

Factors affecting neurological deficits and intractable back pain in patients with insufficient bone union following osteoporotic vertebral fracture

Conversion to hypertrophic vertebral pseudarthrosis following percutaneous vertebroplasty

The use of sintered bone in spinal surgery

Contact Info

Product

Resources

About