The treatment of dysfunctional uterine bleeding with the Mirena IUS: a survival analysis

Abstract

A questionnaire was sent to 124 women with dysfunctional uterine bleeding (DUB) who had been treated with the Mirena IUS. Prior to treatment, the women had received advice about the side effects of the Mirena IUS. There was a 71% response rate of which 21% had the Mirena IUS removed prematurely. The main reasons for removal were pelvic pain and irregular vaginal bleeding. The projected Kaplan-Meier survival rate for the device over the 5-year therapeutic lifetime was 55%. The amenorrhoea rate was 38% and the oligomenorrhoea rate was 72%. The Mirena IUCD is an effective form of treatment for DUB and the majority of women are likely to continue with this treatment at 5 years.

Recent trends in managing abnormal uterine bleeding

“…Studies reported its maximum efficacy 1 year after insertion with a significant reduction of menstrual blood loss upto 97%. 17,20 In Hurskainen et al's trial it was found to be cost effective than hysterectomy. 21…”

Treatment options for dysfunctional uterine bleeding: evaluation of clinical results

“…Studies report reduction of blood loss in menstrual cycles up to 97%, with its maximum efficacy 1 year after insertion [24,[28][29][30][31]. The majority of women with Mirena® bleed only for 1 day or experience just spotting during their period, while 15% of them become amenorrheic [31].…”

Continuation rates and satisfaction with the Levonorgestrel Intrauterine System. Letter to the Editor in response to an article published in volume 31, by Dr. Ewies

“…Ewies does not cite other studies that have shown higher continuation rates in the treatment of HMB [1][2][3][4]. We suggest that it would have been appropriate to compare the continuation rates of the LNG-IUS with a comparator treatment.…”