The Treatment of Adenosis (Adenomatosis) Vaginae

Stabler, Frank

doi:10.1111/j.1471-0528.1967.tb03981.x

Cited by 9 publications

(2 citation statements)

References 3 publications

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“…When such cysts are numerous the surrounding inflammatory reaction may result in the vagina becoming a narrow, rigid tube giving rise to severe dyspareunia. Excision and skin grafting (Stabler, 1967), may then be necessary. None of our benign cases was considered to have sufficiently severe symptoms to justify surgical treatment of this kind, although this treatment was at one time contemplated in Case 4.…”

Section: Discussionmentioning

confidence: 99%

“…Biopsy should then be undertaken in view of the Dossibilitv of Herbst, A. L., and Scully, R. E. (1970): Cancer (Philamalignancy, but if there is no evidence of ;his, definitive surgical treatment may not be required. If it becomes necessary excision and suture of small lesions may be possible, but for truly extensive disease excision and skin grafting as advised by Stabler (1967) is the most appropriate procedure.…”

Section: Discussionmentioning

confidence: 99%

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Vaginal Adenosis: Clinical and Pathological Features With Special Reference to Malignant Change

Blaikley

Dewhurst

Ferreira

et al. 1971

BJOG

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Summary Six cases of vaginal adenosis have been described. In two of them adenocarcinoma of the vagina was present; in one of these clear transition from benign adenosis to carcinoma was evident whilst in the other the association of benign mucous glands with the carcinoma strongly suggests that the latter arose from the former. The first of these patients survived for nine years free from disease and the second died of metastases after 7 years. In a third patient it was thought that early malignant change might be present. Despite the absence of treatment, however, no obvious change has occurred in the lesion over three years and smears have remained negative. The most prominent presenting symptom in the remaining cases was a mucoid vaginal discharge; other important symptoms include dyspareunia and postcoital bleeding. Treatment is discussed.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Vaginal Adenosis: Clinical and Pathological Features With Special Reference to Malignant Change

Blaikley

Dewhurst

Ferreira

et al. 1971

BJOG

View full text Add to dashboard Cite

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Vaginal adenosis and clear cell carcinoma after 5-fluorouracil treatment for condylomas

Goodman

Zukerberg

Nikrui

et al. 1991

Cancer

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Vaginal adenosis and clear cell adenocarcinoma of the vagina occurred in a 44‐year‐old woman after treatment for condylomata acuminata. She had no known exposure to diethylstilbestrol (DES) in utero. Biopsy‐proven vaginal adenosis appeared 8 months after intravaginal 5‐fluorouracil application for recurrent urogenital condylomata acuminata. Forty months later, biopsies showed residual adenosis with foci of clear cell adenocarcinoma. Although clear cell adenocarcinoma is associated with vaginal adenosis and cervical ectropion in DES‐exposed women, its occurrence in adenosis after 5‐fluorouracil therapy has not been reported to the authors' knowledge. In this report, this rare but serious complication of treatment of condylomata acuminata is highlighted, and the literature regarding the development of non‐DES‐associated vaginal adenosis is discussed.

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The incidence and distribution of occult vaginal adenosis

Sandberg

1968

American Journal of Obstetrics and Gynecology

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The Treatment of Adenosis (Adenomatosis) Vaginae

Cited by 9 publications

References 3 publications

Vaginal Adenosis: Clinical and Pathological Features With Special Reference to Malignant Change

Vaginal Adenosis: Clinical and Pathological Features With Special Reference to Malignant Change

Vaginal adenosis and clear cell carcinoma after 5-fluorouracil treatment for condylomas

The incidence and distribution of occult vaginal adenosis

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