An inversion of ISC travel-time data from selected earthquakes in the distance range 30"-90" to 53 stations in Central Europe has been used to model velocity down to 600km depth. The model explains 0.1-0.2 s of the residuals, as for other array studies, leaving 0.5 s unexplained as noise. The uppermost lOOkm of the mantle and crust contains inhomogeneities that correlate remarkably well with the geology. This may be due to deep-seated thermal anomalies or, in some areas, to delays introduced by passage of the rays through sedimentary cover. The deeper anomalies are smaller and unrelated to those in the lithosphere, which suggests that the asthenosphere is decoupled from the rigid lithosphere. The structure at 600 km depth is again quite inhomogeneous and might be due to undulations of the 650km discontinuity. The models show some suggestion of a high velocity slab trending from east to west beneath the Alps.