fMRI can be used to detect asymmetries in memory activation in patients with TLE. Because fMRI studies are noninvasive and provide excellent spatial resolution for functional activation, these preliminary results suggest a promising role for fMRI in improving the preoperative evaluation for epilepsy surgery.

We conducted a retrospective single-blind study assessing the value of MRI in 44 children surgically treated for partial epilepsy, and correlated the MRI findings with the pathology in all cases. MRI revealed abnormalities in concordance with the clinical and electroencephalographic data in 84% of patients. Developmental neuronal migration pathology was present in 25% of patients and was relatively more common in the sensorimotor cortex. There was hippocampal sclerosis in 50% of patients with temporal lobe resection; however, only two of the 10 children with hippocampal sclerosis were below the age of 12 years. Similarly, ganglio-glial tumors were more common than astrocytomas in children below age 12. These results indicate that MRI is sensitive in the detection of pathologic abnormalities in most pediatric candidates for epilepsy surgery, and that the distribution and type of pathology appear to be age related in this population.

Summary. Analysis of NORSAR records and a number of Soviet microfilms reveals second‐mode surface Caves propagating along paths covering a large part of Eurasia. These second modes in the 6–15‐s period band are frequently disturbed by other surface‐wave modes and by body‐wave arrivals. However, in all cases, where the modes appear to be undisturbed and show normal dispersion, the Second Rayleigh modes have a slowly varying phase difference with the Second Love modes. This coupling has the particle motion of Inclined Rayleigh waves characteristic of surface‐wave propagation in anisotropic media, where the anisotropy possesses a horizontal plane of symmetry. Numerical examination of surface wave propagating in Earth models, with an anisotropic layer in the upper mantle, demonstrate that comparatively small thicknesses of material with weak velocity anisotropy can produce large deviations in the polarizations of Inclined Rayleigh Second modes. In many structures, these inclinations are very sensitive to small changes in anisotropic orientation and to small changes in the surrounding isotropic structure. It is suggested that examination of second mode inclination anomalies of second mode surface waves may be a powerful technique for examining the detailed anisotropic structure of the upper mantle.

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Quantitative evidence of hippocampal atrophy has been correlated with site of seizure onset, hippocampal neuronal loss, and seizure relief after resection. Most studies have quantified hippocampal atrophy using ratios or differences between right and left hippocampal values. However, bilateral hippocampal atrophy may remain undetected by these techniques. To assess the frequency and implications of bilateral hippocampal atrophy, we studied absolute hippocampal volumes in 53 temporal lobectomy patients who had undergone intracranial electroencephalogram recordings preoperatively. Coronal images were constructed perpendicular to the longitudinal axis of the hippocampus. Atrophy was defined as > 2 SD below control values in the volume of the posterior 1.5 cm of the hippocampus. Five of 53 patients (9%) had bilateral hippocampal atrophy; four of these cases were undetected by ratios. Surgery was performed on the side of ictal onset in all five patients; four have been seizure-free for > 2 years. These results suggest that (a) mesial temporal sclerosis can be present bilaterally and may go undetected by hippocampal ratio or difference measures; (b) absolute hippocampal volume values as well as ratios are needed to detect all patients with bilateral hippocampal atrophy; and (c) temporal lobectomy is not contraindicated in patients with bilateral hippocampal atrophy, but success depends on electroencephalographic documentation of the side of predominant ictal onset.

A detailed and extensive record section constructed from recordings at the NORSAR array of presumed explosions in continental Russia exhibits two distinct (T, A) triplications. The reliable identification of these upper mantle travel-time branches is possible because of the dense areal sampling of the NORSAR configuration. A simple upper mantle Pvelocity model which can account adequately for the data involves velocity discontinuities at depths of 420 km and 690 km, and fairly uniform velocity gradients elsewhere. For this model, the first arrival branch for A .S 21" extends as a second arrival to a distance of about 33", at which distance it is terminated by the 420-km discontinuity. Rays bottoming between depths of 420 and 690 km span the distance range 16" 5 A 6 28", and give first arrivals in the range 21" 6 A 5 24". Rays which penetrate the 690-km discontinuity give rise to secondary arrivals in the range 19" 5 A 5 25", and first arrivals for distances A 5 25".

The presence of HcA is not an independent predictor of the site of epileptogenesis.