The transport of carotenoids, vitamin A and cholesterol across the intestines of rats and chickens

Ganguly, J.; Krishnamurthy, S.; Mahadevan, S.

doi:10.1042/bj0710756

Cited by 54 publications

(26 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These findings appear paradoxical with lutein diester in diet being hydrolyzed and free lutein in the diet being acylated, but similar interconversions occur when free and esterified cholesterol and free and esterified vitamin A are fed chickens (Ganguly et al, 1957). Regardless of the form of dietary lutein, the intestinal mucosa are bathed in a mixture of free alcohol, monoester, and diester.…”

Section: Discussionmentioning

confidence: 89%

Lutein as a Model Dihydroxycarotenoid for the Study of Pigmentation in Chickens ,

Tyczkowski

Hamilton

1986

Poultry Science

View full text Add to dashboard Cite

A model for the study of pigmentation in young chickens is described in which a white corn-soy based diet supplemented with varying amounts of free lutein (0, 5, 10, 20, 40, and 80 micrograms/g diet) was fed from hatching until 3 weeks of age. The carotenoid content of tissues dissected from chicks of the various groups was measured by high pressure liquid chromatography. In intestinal contents, three forms of lutein were found, with lutein monoester greater than free lutein greater than lutein diester. In the serum, free lutein (96%) and lutein monoester (4%) were found. In the liver, free lutein (80%), monoester (20%), and traces of diester were found. In the integument (toe web), diester greater than monoester approximately equal to free alcohol were found. In each tissue, the concentrations were directly proportional to the dietary concentration of free lutein. The simplest explanation of the data appears to be that part of the free lutein in the diet is esterified during its passage down the intestinal tract and, regardless of its status when absorbed, it is transported in the body as the free alcohol. When it enters depot sites such as the integument, lutein is deposited mainly as esters, presumably as the result of local enzymatic activity.

show abstract

Section: Discussionmentioning

confidence: 89%

Lutein as a Model Dihydroxycarotenoid for the Study of Pigmentation in Chickens ,

Tyczkowski

Hamilton

1986

Poultry Science

View full text Add to dashboard Cite

show abstract

“…The ability of domestic chickens to readily absorb dietary carotenoids (oxycarotenes such as lutein, zeaxanthin, and canthaxanthin) is well known (Ganguly et al, 1959;Quackenbush et al, 1965;Tyczkowski and Hamilton, 1986), and in many parts of the United States there is a consumer preference for poultry meat products pigmented by metabolic deposition of these compounds in skin and muscle. An increase in dietary fat, particularly triglycerides, is reported to increase absorption of these carotenoids (Hamilton, 1985).…”

Section: Introductionmentioning

confidence: 98%

Effect of Atherogenic Diet on Chicken Plasma Lipids and Lipoproteins

Allen

Wong

1993

Poultry Science

View full text Add to dashboard Cite

Adult male White Leghorn chickens were used in an experimental model system to study atherogenesis, and the effects of an atherogenic diet on plasma lipoprotein composition including carotenoids were determined. This model also included treatment with diazepam, a drug known to reduce formation of atherogenic plaques. After 6 wk consumption of a high-cholesterol, high-triglyceride diet, chickens had mean total plasma cholesterol, triglyceride, and carotenoid concentrations that were significantly increased over those from chicks that consumed the standard diet. Diazepam treatment had no significant effect on whole plasma concentrations of these lipids. Total body weight gain was unaffected by diet, but liver weight expressed as percentage of body weight was significantly increased in chickens that consumed the atherogenic diet. High density lipoprotein (HDL) and low density lipoprotein (LDL) fractions were isolated from plasma samples by ultracentrifugation. The atherogenic diet increased the carotenoid, cholesterol, and protein content of the LDL fractions but not the HDL fractions.

show abstract

“…Hens providing eggs for hatching were fed a white cornsoy diet (Table 1) for 6 wk prior to collecting eggs for hatching in order to deplete the maternal stores of tissue carotenoids. This resulted in egg yolks and progeny having minimal concentrations of nonspecific carotenoids (Ganguly et al, 1957). All chicks were brooded in electrically heated batteries under continuous lighting with feed and water available ad libitum until they were 3 wk old, at which time the experiment was ended.…”

Section: Methodsmentioning

confidence: 99%

Metabolism of Canthaxanthin, a Red Diketocarotenoid, by Chickens

1988

View full text Add to dashboard Cite

Canthaxanthin, (4,4'-diketo-beta,beta-carotene), a red carotenoid used to extend the dominant wavelength of the yellow pigments in the skin and egg yolk of chickens, was fed (70 micrograms/g diet) to chicks depleted of normal tissue oxycarotenoids. High performance liquid chromatography analysis of tissues from such chicks revealed that a portion of canthaxanthin was reduced to 4-hydroxyechinenone (4-hydroxy-4'-keto-beta,beta-carotene) that in turn was reduced in part to isozeaxanthin (4,4'-dihydroxy-beta,beta-carotene). The alcohols thus formed were acylated in part to 4-hydroxyechinenone monoester and isozeaxanthin monoester and diester. Individual metabolites were identified by retention times, ratios A470/A430, and stopped-flow spectral analyses, which were identical in each case to authentic standards. Ratios of canthaxanthin to metabolites varied with the tissue, but in general metabolites were concentrated in the integument.

show abstract

The transport of carotenoids, vitamin A and cholesterol across the intestines of rats and chickens

Cited by 54 publications

References 14 publications

Lutein as a Model Dihydroxycarotenoid for the Study of Pigmentation in Chickens ,

Lutein as a Model Dihydroxycarotenoid for the Study of Pigmentation in Chickens ,

Effect of Atherogenic Diet on Chicken Plasma Lipids and Lipoproteins

Metabolism of Canthaxanthin, a Red Diketocarotenoid, by Chickens

Contact Info

Product

Resources

About