The Trace Detection of Nitrite Ions Using Neutral Red Functionalized SH-β-Cyclodextrin @Au Nanoparticles

Abstract

A novel fluorescence sensor of NR-β-CD@AuNPs was prepared for the trace detection of nitrite in quantities as low as 4.25 × 10−3 μg∙mL−1 in an aqueous medium. The fluorescence was due to the host-guest inclusion complexes between neutral red (NR) molecules and gold nanoparticles (AuNPs), which were modified by per-6-mercapto-beta-cyclodextrins (SH-β-CDs) as both a reducing agent and a stabilizer under microwave radiation. The color of the NR-β-CD@AuNPs changed in the presence of nitrite ions. A sensor was applied to the determination of trace nitrites in environmental water samples with satisfactory results.

Gold Nanomaterials and Bone/Cartilage Tissue Engineering: Biomedical Applications and Molecular Mechanisms

“…For gold nanomaterials, AuNPs, as well as nanoclusters (AuNCs), nanocages, nanorods (AuNRs), nanobelts, nanoplates and so on, are becoming increasingly popular because of their optical nonlinearities (Gao et al, 2015;Huang et al, 2017;Zhang et al, 2018), local surface plasmon resonance (SPR) (Li Q. et al, 2017) and photothermal effect (Jiang et al, 2012). Considering these characteristics, it has been proved that gold nanomaterials can be used in many fields such as chemistry, biomedicine, including the diagnosis and treatment of diseases (Li et al, 2018b), sensor (Li et al, 2015), catalysis (Li et al, 2013), surface-enhanced Raman spectroscopy (Huang et al, 2019), illumination (Zhang et al, 2017b), detector (Du et al, 2018), and therapy (Yeh et al, 2012). The easy of synthesis and the unique properties of gold nanomaterials make them ideal candidates for translation from the laboratory scale into the clinical arena for use in humans.…”

Bio-Doped Microbial Nanosilica as Optosensing Biomaterial for Visual Quantitation of Nitrite in Cured Meats

“…However, the diazotization of alkylanilines reached equilibrium only after 60 min. A fluorimetric nitrite biosensor with polythienothiophene-fullerene thin film detectors based on integrated polymer photodetectors to detect light from fluorescence reactions with a diaminofluorescein probe [ 52 ], and fluorescence detection of nitrite by using neutral red (NR) molecules and gold nanoparticles (AuNPs), which were modified by per-6-mercapto-beta-cyclodextrins (SH-β-CDs), and changed in color in the presence of trace amount of nitrite [ 53 ], were able to detect nitrite to a submicromolar concentration. Nevertheless, these methods were confined to a narrow nitrite linear detection range at low levels.…”

The Colorimetric Identification of NO2− in Latent Fingerprints by Hydroxypropyl‐β‐cyclodextrin

“…The specific recognition of the subject (receptor) to the guest (substrate) [9] is realized. As the current literature reports, supramolecular recognition of inorganic salts, [10] proteins, [11] amino acids, [12] drugs, [13] poisons, [14] explosives, [15] and other objects has been realized. Cyclodextrin, as a kind of supramolecule, not only has the properties of supramolecule, but also the hydroxyl groups at the edge of its cavity can form hydrogen bonds, resulting in electrostatic and dipole interactions with other molecules [16] .…”