The Toxicology of Dieldrin and Its Bearing on Field Use of the Compound 1

Hayes, Wayland J.; Ferguson, Frederick; Cass, Jules S.

doi:10.4269/ajtmh.1951.s1-31.519

Cited by 7 publications

(1 citation statement)

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“…It has been shown by direct measurement that the absorption of dieldrin from the intestinal tract varies with the vehicle (7), but it is freely absorbed from the skin even without a solvent (12).…”

Section: Hayesmentioning

confidence: 99%

Review of the Metabolism of Chlorinated Hydrocarbon Insecticides Especially in Mammals

Wj¹

1965

Annu. Rev. Pharmacol.

119

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This review discusses the absorption, storage, biotransformation, and excretion of chlorinated hydrocarbon insecticides; thus, it emphasizes those aspects of physiology that can be studied by the methods of analytical or ganic chemistry. The broader aspects of toxicity, as they relate to the me tabolism of these materials, were discussed by Winteringham & Barnes (1).This review emphasizes mammalian metabolism of the compounds, but con tains some information on their metaboli sm by other organisms, a subject that has already been reviewed by Perry (2). In relation to mammals, great est interest centers in numerous repeated doses that produce no obvious in jury and that are so small that they might be encountered under practical conditions in the use of insecticides. For this reason, DDT and related re sidual insecticides are emphasized, but some information is given on the chlorinated hydrocarbon fumigants.

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Section: Hayesmentioning

confidence: 99%