The topographical features of EEGs in patients with affective disorders

Kano, Kunio; Nakamura, Michihiko; Matsuoka, Teruyuki; Iida, Hideharu; Nakajima, Teruo

doi:10.1016/0013-4694(92)90025-d

Cited by 68 publications

(49 citation statements)

References 10 publications

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“…In agreement with prior findings [6,[18][19][20][21], depressed patients differed from healthy controls in resting anterior EEG asymmetry when data were collapsed across the two recording sessions separated by 2-4 weeks. Depressed patients failed to show more left than right anterior alpha activity, whereas healthy controls had markedly more right than left anterior alpha activity, i.e.…”

Section: Discussionsupporting

confidence: 78%

“…Similar relations of BDI scores to anterior EEG asymmetry were also reported for healthy men [13]. Among clinically depressed patients, there is ample evidence of left-sided [17] or left anterior hypoactivation [6,[18][19][20][21], although there are also several contradictory findings [22][23][24]. However, studies differ widely in EEG methodology (e.g.…”

Section: Introductionmentioning

confidence: 50%

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Is Resting Anterior EEG Alpha Asymmetry a Trait Marker for Depression?

Beauducel²,

et al. 2000

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Several lines of evidence suggest that asymmetric anterior brain activation is related to affective style, linking left hemisphere activation to positive affect and right hemisphere activation to negative affect. However, previous reports of left frontal hypoactivation in depressed patients were not confirmed in recent studies. This study evaluated additional characteristics of resting EEG alpha (8–13 Hz) asymmetry in 15 clinically depressed patients and 22 healthy adults by recording EEG activity on two separate occasions, 2–4 weeks apart. Across both sessions, group differences in anterior EEG asymmetry were compatible with the original hypothesis. However, groups differed in temporal stability of anterior EEG asymmetry, which was retest reliable in controls but not depressed patients. In contrast, temporal stability of posterior EEG asymmetry was acceptable in both groups. Increased variability of anterior EEG asymmetry may be a characteristic feature for depression, and, if so, this would challenge the notion that anterior EEG alpha asymmetry is a trait marker for depression.

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Section: Discussionsupporting

confidence: 78%

Section: Introductionmentioning

confidence: 50%

Is Resting Anterior EEG Alpha Asymmetry a Trait Marker for Depression?

Beauducel²,

et al. 2000

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“…Additionally, bipolar disorder patients with decreased functional network integration and decreased optimal balance of network segregation in functional fronto-central and centro-parietal networks had higher depression scores (see Kim et al 2013). In the manic phase, various frequency characteristics can be observed during rest (see Clementz et al 1994;Kano et al 1992), with increased 'busy thinking' related, beta activity correlating with increased mania symptoms (Kam et al 2013). Increased left-dominant, goal striving frontal alpha asymmetry, relative to controls, appears to be characteristic of mania (HarmonJones et al 2008;Nusslock et al 2012), opposing the activity characterizing the depressed phase.…”

Section: Treatmentmentioning

confidence: 95%

Physiological Correlates of Bipolar Spectrum Disorders and their Treatment

Outhred

Kemp

Malhi

2014

Electrophysiology and Psychophysiology in Psychiatry and Psychopharmacology

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Bipolar spectrum disorders (BSDs) are associated with great personal and socioeconomic burden, with patients often facing a delay in detection, misdiagnosis when detected, and a trial-and-error approach to finding the most appropriate treatment. Therefore, improvement in the assessment and management of patients with BSDs is critical. Should valid physiological measures for BSDs be identified and implemented, significant clinical improvements are likely to be realized. This chapter reviews the physiological correlates of BSDs and treatment, and in doing so, examines the neuroimaging, electroencephalogram, and event-related potential, and peripheral physiological correlates that both characterize and differentiate BSDs and their response to treatment. Key correlates of BSDs involve underlying disturbances in prefrontal and limbic network neural activity, early neural processing, and within the autonomic nervous system. These changes appear to be mood-related and can be normalized with treatment. We adopt an "embodied" perspective and propose a novel, working framework that takes into account embodied psychophysiological mechanisms in which the physiological correlates of BSD are integrated. This approach may in time provide the objective physiological measures needed to improve assessment and decision making when treating patients with BSDs. Future research with integrative, multimodal measures is likely to yield potential applications for physiological measures of BSD that correlate closely with diagnosis and treatment.

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“…In another study drawing attention to the relation between negative family history and abnormal EEG (electroencephalography), small sharp spikes were demonstrated in nearly half of these cases (Kano, Nakamura, & Matsuoka, 1992). In some studies, relation was found between being refractory to treatment and some disorders in the form of sleep spindles detected in the awake EEG of some patients (Hudson, Lipinski, & Frankenburg, 1988).…”

Section: Introductionmentioning

confidence: 99%

EEG (Electroencephalography) Abnormality in First Episode Mania: Is It Trait or State?

Kesebir¹,

Güven²,

Yaylacı³

et al. 2013

JPR

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The aim of this study is to investigate the frequency of abnormal EEG (electroencephalography) findings in first episode mania and to determine whether EEG abnormality improves at the subsequent remission period. The secondary, to compare cases with or without abnormal EEG findings with regard to clinical characteristics of BD (bipolar disorder). In the present study, 86 consecutive first attack mania cases between the ages of 18-65 diagnosed as BD, manic episode according to DSM-IV who referred to our outpatient clinic or emergency service whose informed consent form was signed by first degree relatives were evaluated. Inclusion criteria were not having previous depressive episode, absence of any neurologic disorder, especially epilepsy, absence of history head trauma, and/or loss of consciousness and were not using any drugs which can influence electroenecepholafraphic activity before EEG (antiepileptic, anxiolytic, antidepressant, and antipsychotics). Diagnostic interviews were made with SCID-I (DSM-IV Structured Clinical Interview) and information on disease was recorded with SKIP-TURK (Mood Disorder Diagnosis and Follow-up Form). EEG recordings were made withdigital EEG device in 16 channels. EEG abnormality is more frequent in mania than remission period (p = 0.022) and occurs at the rate of 28.7%. All cases with continuing abnormal EEG findings in remission period are women.In cases with continuing EEG abnormality, the age of menarche is smaller (p = 0.032) but family history is less frequent (p = 0.008). Childhood trauma and history of suicide attempt is more frequent in cases with abnormal EEG in remission period as well (p < 0.001 and 0.005). Of the cases, whose abnormal EEG improved in remission period, 83.3% were treated with anticonvulsants. In some bipolar cases, abnormal EEG is present from the onset of disease and it is associated with some clinical characteristics. Abnormal EEG returns to normal in half of the cases in remission period.

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The topographical features of EEGs in patients with affective disorders

Cited by 68 publications

References 10 publications

Is Resting Anterior EEG Alpha Asymmetry a Trait Marker for Depression?

Is Resting Anterior EEG Alpha Asymmetry a Trait Marker for Depression?

Physiological Correlates of Bipolar Spectrum Disorders and their Treatment

EEG (Electroencephalography) Abnormality in First Episode Mania: Is It Trait or State?

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