The Thiamine Requirement of the Normal Infant

Holt, L. Emmett; Nemir, Rosa Lee; Snyderman, Selma E.; Albanese, Anthony A.; Ketron, Katherine C.; Guy, Loren P.; Carretero, Rosario

doi:10.1093/jn/37.1.53

Cited by 25 publications

(2 citation statements)

References 8 publications

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“…It is difficult to reconcile the association of zero values for thiamine with the observed levels for riboflavin, except by suggesting that (a) riboflavin causes inherent errors in the thiochrome assay for thiamine; or (b) these subjects were truly deficient in thiamine and that, under these conditions, riboflavin excretion increased. On the other hand, the transketolase criteria were based upon the relationship between the transketolase TPP‐effect values and the onset of loss of appetite and weight in volunteers receiving thiamine‐low diets at a time when urinary thiamine had reached the minimal excretion level defined by Holt et al (25). It should be emphasized, too, that thiamine synthesis and particularly the utilization of endogenously synthesized thiamine (as measured by urinary excretion) is extremely variable in man (26).…”

Section: Resultsmentioning

confidence: 99%

Evaluation of the Nutritional Status of Elderly Subjects, With a Comparison Between Fall and Spring*

Dibble

Brin

Thiele

et al. 1967

J American Geriatrics Society

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Section: Resultsmentioning

confidence: 99%

Evaluation of the Nutritional Status of Elderly Subjects, With a Comparison Between Fall and Spring*

Dibble

Brin

Thiele

et al. 1967

J American Geriatrics Society

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“…Some studies attempted to estimate thiamin requirement of infants (Holt et al., ) and children (Dick et al., ) based on the changes in urinary excretion of thiamin in response to controlled amounts of dietary thiamin. In these studies, the level of thiamin intake associated with ‘minimal’ urinary thiamin excretion was used as a criterion to define thiamin requirement.…”

Section: Criteria (Endpoints) On Which To Base Dietary Reference Valuesmentioning

confidence: 99%

Dietary reference values for thiamin

Turck¹,

Bresson²,

Burlingame³

et al. 2016

EFS2

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Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) derived dietary reference values (DRVs) for thiamin (vitamin B1). The Panel considers that data from depletion-repletion studies in adults on the amount of dietary thiamin intake associated with the erythrocyte transketolase activity coefficient (aETK) < 1.15, generally considered to reflect an adequate thiamin status, or with the restoration of normal (baseline) erythrocyte transketolase activity, without a sharp increase in urinary thiamin excretion, can be used to estimate thiamin requirement. In the absence of new scientific evidence, the Panel endorses the average requirement (AR) of 0.072 mg/MJ (0.3 mg/1,000 kcal) for all adults proposed by the Scientific Committee for Food (SCF) in 1993 on the basis of one depletion-repletion study, in which both aETK and urinary thiamin excretion were measured. Results from other depletion-repletion studies are in agreement with this value. The Panel agrees on the coefficient of variation of 20% used by the SCF to cover uncertainties related to distribution of thiamin requirements in the general population, and endorses the population reference intake (PRI) of 0.1 mg/MJ (0.4 mg/1,000 kcal) set by the SCF for all adults. The same AR and PRI as for adults, expressed in mg/MJ, are proposed for infants aged 7-11 months, children aged 1 to < 18 years, and during pregnancy and lactation, under the assumption that the relationship between thiamin requirement and energy requirement is the same in all population groups. Acknowledgements: The Panel wishes to thank EFSA member of staff Fanny H eraud for the support provided to this scientific opinion.

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Fasting in obesity. Thiamine depletion as measured by erythrocyte transketolase changes

Haro¹

1966

Archives of Internal Medicine

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The Thiamine Requirement of the Normal Infant

Cited by 25 publications

References 8 publications

Evaluation of the Nutritional Status of Elderly Subjects, With a Comparison Between Fall and Spring*

Evaluation of the Nutritional Status of Elderly Subjects, With a Comparison Between Fall and Spring*

Dietary reference values for thiamin

Fasting in obesity. Thiamine depletion as measured by erythrocyte transketolase changes

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