Fasting in obesity. Thiamine depletion as measured by erythrocyte transketolase changes

Pentose-Phosphate Pathway of Erythrocytes in Metabolic Diseases

“…It should be noted in this context, however, that red cell TKA determinations are at present widely used to diagnose thiamine deficiency. It has been shown that fasting or reduced nutrition in a few weeks may reduce the red cell TKA [7], The diet of alcoholics is known to be un balanced and often defective for long periods, and for these reasons they may be deficient in thiamine. On the other hand it has been shown [5] that experimental liver damage reduced the TKA of red cells.…”

Low Plasma Levels of Vitamin A and E during Weight Reduction

“…Much attention has been paid in the past to the effect of weight reduction on atherosclerotic risk factors and numerous reports have been published regarding protein and carbohydrate metabolism in obese subjects. Very few studies have evaluated the vitamin status of patients undergoing rapid and/or longterm weight reduction, particularly in grossly obese children and adolescents (1,2).…”

Evaluation of the Nutritional Status of Elderly Subjects, With a Comparison Between Fall and Spring*

“…Comment should be made on certain relationships between low urinary values of thiamine and normal or high riboflavin excretion levels (22)(23)(24). Presented in Table 14 are data on the riboflavin excretion in all subjects for whom zero levels of thiamine excretion were found.…”