The technique for human embryo transfer

Leeton, John; Trounson, Alan; Jessup, D. S. D.; Wood, Carl

doi:10.1016/s0015-0282(16)46451-4

Cited by 119 publications

(37 citation statements)

References 14 publications

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“…Most IVF teams consider not touching the endometrium and the uterine fundus with replacement of the embryos in the lumen of the endometrial cavity the most important factors for successful embryo transfer [20,21]. It has been traditionally accepted that the embryo should be placed ∼ 10 mm below the fundal endometrial surface [22], some authors have suggested that placing embryos rather lower in the uterine cavity may improve pregnancy rate [23]. The aim of our study was to assess the importance of the depth of embryo replacement into the uterine cavity measured by ultrasound and its influence on implantation rate after IVF.…”

Section: Introductionmentioning

confidence: 99%

The impact of the depth of embryo replacement on IVF outcome

Pacchiarotti

Mohamed

Micara

et al. 2007

J Assist Reprod Genet

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Purpose: To evaluate the effect of the depth of embryo transfer replacement on clinical pregnancy rate.Methods: Data from a total of 104 consecutive embryo transfers performed on 104 womenn aged 26-37 years were prospectively collected for this study. All patients underwent a standard down regulation protocol for ovarian stimulation. Oocytes retrieval were performed at 36 h after hCG administration. Embryo transfer took place at 48 h after insemination. The patients were matched in two groups according to the distance between the tip of the catheter and the uterine fundus at transfer (group A > 10 < 15 mm and group B ≤ 10 mm). The same method of loading embryos into the embryo transfer catheter was used.Results: Clinical pregnancy rates varied significantly (p ≤ 0.05) between the two groups: 27.7% in group A and 14% in group B. The number and quality of embryos transferred did not differ between the groups.Conclusions: The results suggest that the depth of embryo replacement may be an important variable in embryo transfer technique.

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Section: Introductionmentioning

confidence: 99%

The impact of the depth of embryo replacement on IVF outcome

Pacchiarotti

Mohamed

Micara

et al. 2007

J Assist Reprod Genet

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“…Compared with the traditional method, abdominal ultrasound-guided embryo transfer has a number of potential benefits (Hearns-Stokes et al, 2000;Leeton et al, 1982;Nabi et al, 1997;Sallam et al, 2002). First, with the guidance of ultrasound, the catheter can be bent to easily pass through the cervical canal and follow the uterine axis, which helps avoid overstimulation and reduction in incidence of difficult transfers, endometrial trauma (Letterie et al, 1999;Woolcott and Stanger, 1997), and bleeding ( Goudas et al, 1998;Nabi et al, 1997;Sallam et al, 2002) that can cause excessive fundo-uterine contractions at the time of embryo transfer has been associated with lower clinical pregnancy rates (Goudas et al, 1998;Sallam et al, 2002).…”

Section: Resultsmentioning

confidence: 99%

“…Physicians may argue that UGET has additional benefits over UTT other than the diagnosis of a trial transfer inaccuracy. The evidence from studies would imply that the addition of ultrasound guidance during trial transfer would further reduce the benefit of UGET when used routinely ( Diedrich et al, 1989;Englert et al, 1986;Ghazzawi et al, 1999;Goudas et al, 1998;Hearns-Stokes et al, 2000;Leeton et al, 1982;Wood et al, 1985).…”

Section: Ultrasound and Embryo Transfermentioning

confidence: 99%

The Role of Ultrasound in the Evaluation of Endometrial Receptivity Following Assisted Reproductive Treatments

Ivanovski¹

2012

In Vitro Fertilization - Innovative Clinical and Laboratory Aspects

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“…Only one sperm penetrates the oocyte, and fertilization occurs. The resulting zygote continues its journey down the fallopian tube for 2-3 days and, during its transit, continues to divide into approximately [8][9][10][11][12][13][14][15][16] cells. The pre-embryo then enters the uterus in the blastocyst stage and after 2-3 days it implants itself in the uterus and grows over the next 39 weeks.…”

Section: Normal (Coital) Reproductionmentioning

confidence: 99%

“…Usually up to 2-3 pre-embryos are transferred to maximize the chance of a successful implantation/pregnancy. 10 A "chemical pregnancy" is said to have occurred if the pregnancy test becomes positive, but a "clinical pregnancy" is said to have occurred when ultrasonography shows an embryo with cardiac activity, usually 4-5 weeks after the transfer.…”

Section: Embryo Transfermentioning

confidence: 99%

Islamic Shari'ah Rulings on New Reproductive Choices

Fadel

2005

J Islam Med Assoc

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Infertility is a serious hardship. There have been several advancements in its management. A major breakthrough in 1978 was the successful achievement of pregnancy and the birth of a girl as a result of In Vitro Fertilization (IVF). That success led to several technological innovations that heralded a new era of "Non Coital Reproduction". These methods are collectively known as "Assisted Reproductive Technologies (ARTs)." These are now available to women all across the USA and in many other countries. Thousands of couples are achieving pregnancies through the use of ARTs every year. Most of these couples would otherwise never have achieved pregnancies.Although this is a welcome addition to the medical armentarium, there are several unresolved ethical, societal and religious concerns about their applications, especially in regards to the more recent applications of IVF.A brief account of "normal" procreation and the basic principles of ARTs are given. Then the sharfa (Islamic law) principles that guide us in deciding the acceptability of these technologies will be discussed. Then the rulings that have been agreed upon by Islamic scholars will be given. Briefly stated, Islam not only allows but also encourages married couples to seek treatment of infertility, including the use of ARTs. However, certain limits cannot be crossed. The Islamic principles that identify these limits are 1) a valid marriage contract; 2) preservation of lineage including adopted offspring; 3) surrogacy is prohibited and the "birth mother" is the mother; and 4) gametes are not to be donated.

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The technique for human embryo transfer

Cited by 119 publications

References 14 publications

The impact of the depth of embryo replacement on IVF outcome

The impact of the depth of embryo replacement on IVF outcome

The Role of Ultrasound in the Evaluation of Endometrial Receptivity Following Assisted Reproductive Treatments

Islamic Shari'ah Rulings on New Reproductive Choices

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