The systemic treatment of onychomycosis

Wenig, Jay A.

doi:10.1016/j.cpm.2004.05.003

Cited by 7 publications

(7 citation statements)

References 44 publications

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“…Es fungistática contra levaduras y mohos no dermatofitos, y fungicida contra dermatofitos 41 . Es efectiva contra C. parapsilosis y tiene menos actividad contra C. albicans 1,52 . Este medicamento ha demostrado ser el de elección por tener una eficacia superior a los otros tratamientos orales, ser bien tolerado y tener pocas interacciones farmacológicas a pesar de ser un inhibidor del citocromo p450 40,51 .…”

Section: Tratamiento Oralunclassified

“…Es activo contra dermatofitos, mohos y Candida spp. 47,52 . Aunque la terbinafina es más costo-efectiva, el itraconazol tiene un espectro de actividad antifúngica más amplio y podría considerarse en el tratamiento de infecciones por mohos y Candida spp.…”

Section: Tópica Oralunclassified

“…Una de sus ventajas es que puede administrarse una vez a la semana. Su eficacia en el tratamiento de la onicomicosis es moderada y las tasas de curación van del 15 al 61 % 47,52 . Aún no ha sido aprobado por la FDA para el tratamiento de la onicomicosis 52 .…”

Section: Tópica Oralunclassified

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Onicomicosis: afección común de difícil tratamiento

Mendoza¹,

Palacios²,

Cardona³

et al. 2012

rev. asoc. colomb. dermatol. cir. dematol.

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La onicomicosis es la enfermedad más frecuente de las uñas. Es una infección de la unidad ungular causada por dermatofitos, mohos y levaduras, de los cuales, los primeros son los agentes causales más frecuentes a nivel mundial. Sin embargo, la epidemiología puede variar de acuerdo con la ubicación geográfica y el clima. En el presente manuscrito se presenta una revisión de la literatura científica sobre la epidemiología, las presentaciones clínicas, el diagnóstico y el tratamiento de las onicomicosis.

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Section: Tratamiento Oralunclassified

Section: Tópica Oralunclassified

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Onicomicosis: afección común de difícil tratamiento

Mendoza¹,

Palacios²,

Cardona³

et al. 2012

rev. asoc. colomb. dermatol. cir. dematol.

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“…Serious adverse events associated with griseofulvin are uncommon. Mild side effects, most commonly headache and gastrointestinal disturbance, occur in about 15% of patients (47). Photosensitivity and hepatoxicity occur less commonly.…”

Section: Oral Antifungal Therapymentioning

confidence: 99%

Toenail onychomycosis: current and future treatment options

2007

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Onychomycosis is a common disease affecting as much as 8% of the general population. Treatment of onychomycosis is challenging, complicated by low cure rates and relatively high relapse rates. This paper reviews the efficacy of current oral, topical, and surgical treatment options. Currently, the treatment of choice for toenail onychomycosis is oral terbinafine because of its high efficacy, low relapse rates, and cost-effectiveness. Oral itraconazole or fluconazole could be considered for infections caused by Candida. Topical therapies may be a useful adjunct to these systemic therapies, but are less effective when used alone. More research is needed to determine the best measures for preventing reinfection.

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“…The most common form of fungal infection is that caused by dermatophytes. 3 Nail ringworm causes nail infections when left untreated for a long period of time. 1,6,11 Bacteria are most abundant in Trichophyton rubum, and nail mycosis is a general term for infections caused by other fungi such as ringworm and Candida.…”

mentioning

confidence: 99%

Current therapeutic insights regarding problematic fingernails and toenails in the Republic of Korea

Lee

Kwon

2022

J of Cosmetic Dermatology

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Problematic nails and toenails are infected by bacteria, and if left untreated for a long time, they become discolored, deformed, or problematic nails due to various diseases. 1 Athlete's foot is considered to be the most negative factor when considering foot health.Most people have made many efforts, such as trying to get rid of athlete's foot, which has symptoms of athlete's foot peeling and hardening. Nonetheless, athlete's foot does not disappear easily, and many modern people are looking for ways to improve it. 2,3 Nail mycosis, in addition to the cosmetological aspects of the nail, can result in functional impairment of the nail and can be transmitted to others, so treatment is needed. [4][5][6] Nowadays, there is a tendency to emphasize appearance, and if there is a deformation in the nail, not only is it impaired the performance of an individual's work, but it also causes a temporary deterioration in the quality of life. 7 The number of problematic nails is increasing due to the increase in the elderly population, the high prevalence of diabetes, the increase in the use of immunosuppressive drugs and anti-biotics, and the increase in exposure to infectious strains. Interest in treatment is increasing as the target level rises and the weight of care increases. 8 However, despite the many developments in therapeutic agents, it shows a problem that it takes a long time to be completely cured, the recurrence rate is high, and it often fails. 9 | ONYCHOMYCOS IS KOH TE S T AND FUNG AL CULTURE TE S TOnychomycosis is a disease in which the nail is invaded by fungi, such as dermatophytes, yeasts, and non-dermatophytes, and is a very common disease that accounts for about 50% of all nail

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The systemic treatment of onychomycosis

Cited by 7 publications

References 44 publications

Onicomicosis: afección común de difícil tratamiento

Onicomicosis: afección común de difícil tratamiento

Toenail onychomycosis: current and future treatment options

Current therapeutic insights regarding problematic fingernails and toenails in the Republic of Korea

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