“…Treating methylthiadiazole 112 with aromatic carboxylic acid esters 113a – 113g in the presence of sodium hydride got the methyl group substituted. In addition, reacting with acyl chloride 115 in the presence of triethylamine gives rise to formation of mixtures of diacylated thiadiazoles 116 and 117 ; generally the latter is rearranged on heating in higher boiling solvents to give 116 (Schemes d and ) …”
Section: Reactivity and Synthetic Application Of 134-thiadiazolementioning
confidence: 99%
“…In addition, reacting with acyl chloride 115 in the presence of triethylamine gives rise to formation of mixtures of diacylated thiadiazoles 116 and 117; generally the latter is rearranged on heating in higher boiling solvents to give 116 (Schemes 24d and 25). 85 3.2.2. Reactivity of Halogens Attached to the Ring Carbon Atom.…”
Section: Reactivity Of the Ring Carbon Atommentioning
“…Treating methylthiadiazole 112 with aromatic carboxylic acid esters 113a – 113g in the presence of sodium hydride got the methyl group substituted. In addition, reacting with acyl chloride 115 in the presence of triethylamine gives rise to formation of mixtures of diacylated thiadiazoles 116 and 117 ; generally the latter is rearranged on heating in higher boiling solvents to give 116 (Schemes d and ) …”
Section: Reactivity and Synthetic Application Of 134-thiadiazolementioning
confidence: 99%
“…In addition, reacting with acyl chloride 115 in the presence of triethylamine gives rise to formation of mixtures of diacylated thiadiazoles 116 and 117; generally the latter is rearranged on heating in higher boiling solvents to give 116 (Schemes 24d and 25). 85 3.2.2. Reactivity of Halogens Attached to the Ring Carbon Atom.…”
Section: Reactivity Of the Ring Carbon Atommentioning
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