The Synergistic Effect of Hydroalcoholic Extracts of
 Origanum Vulgare
 ,
 Hypericum Perforatum
 and Their Active Components Carvacrol and Hypericin Against
 Staphylococcus Aureus

Bahmani, Mahmoud; Taherikalani, Morovat; Khaksarian, Mojtaba; Rafieian-Kopaei, Mahmoud; Ashrafi, Behnam; Nazer, Mohammadreza; Soroush, Setareh; Abbasi, Naser; Rashidipour, Marzieh

doi:10.4155/fsoa-2018-0096

Cited by 40 publications

(27 citation statements)

References 34 publications

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“…The plant has anti-inflammatory, antibacterial, antioxidant, anticancer, analgesic and neuroprotective as well as wound healing effects [25]. Spathulenol, caryophyllene oxide, linalool, alpha-terpineol, trans-caryophyllene and geraniol alpha-phellandrene, beta-myrcene and trans-caryophyllene can be active ingredients of these two plants that have the above-mentioned therapeutic effects [26][27][28][29][30][31][32][33]. Studies have shown that medicinal plants have both traditional and modern research with the use of stand-alone medicinal and therapeutic effects and their beneficial effects through their active ingredients.…”

Section: Discussionmentioning

confidence: 99%

Study of extraction and chemical compounds of Scrophularia striata Boiss. and Scrophularia deserti Delile using HS-SPME and GC-MS

Bahmani

Hadavi

Abbasi

2020

Plant Biotechnol Persa

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In this study, from June 2019 to May 2019 aerial parts of Scrophularia striata Boiss. were collected from Ilam city and those of Scrophularia deserti Delile from Dehloran city, Ilam province in western Iran. The aerial parts of the medicinal plants were pulverized. The essential and volatile oils were extracted by headspace solid-phase microextraction (HS-SPME) and their chemical compounds analyzed by Gas chromatography-mass spectrometry (GC-MS). Using HS-SPME, 68 and 49 chemical compounds were identified from S. striata and S. deserti, respectively. Spathulenol (18.41%) was the highest chemical compound of the essential oil of S. striata, followed by caryophyllene oxide (15.38%), linalool (11.85%), alpha-terpineol (8.34%), trans-caryophyllene (4.44%) and geraniol (3.10%). The most important identified compounds from S. deserti were caryophyllene oxide (15.38%), linalool (11.85%), alpha-terpineol (8.34%), trans-caryophyllene (4.44%) and geraniol (3.10%). The most important chemical compounds of S. deserti essential oil included alpha-pinene (25.54%), alpha-phellandrene (19.60%), beta-myrcene (11.29%) and trans-caryophyllene (6.78%). Results show major constituents of this two plant include with a high amount of Spathulenol and caryophyllene oxide has high pharmaceutical and healthful value.

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Section: Discussionmentioning

confidence: 99%

Study of extraction and chemical compounds of Scrophularia striata Boiss. and Scrophularia deserti Delile using HS-SPME and GC-MS

Bahmani

Hadavi

Abbasi

2020

Plant Biotechnol Persa

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“…It has been widely claimed that when food ingredients are mixed rather than using a single material, the synergistic therapeutic effects due to the combination of biochemicals may be superior to that of single biochemicals [ 20 , 21 ]. Much research has reported that when the mixed material is treated, a more effective bioactive effect is exhibited than when a single material is treated [ 22 , 23 , 24 ]. In this study, we aimed to establish a mixing ratio that dramatically enhanced immune function by utilizing two natural resources of Jeju, FES and SQN.…”

Section: Introductionmentioning

confidence: 99%

Enhancement of Immune Activities of Mixtures with Sasa quelpaertensis Nakai and Ficus erecta var. sieboldii

Kwon

Choi

Han

et al. 2020

Foods

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The objective of the present study was to develop a concoction of natural products that could dramatically improve immune function with minimal possible side effects. Sasa quelpaertensis Nakai and Ficus erecta var. sieboldii are plants that are native to Jeju Island, Korea and are known to be rich in physiologically active substances. We prepared a mixture of different proportions and extraction conditions using two natural plants and determined their optimum mixing ratio and extraction method by assessing immune function-related biomarkers in RAW264.7 macrophages. Optimal extract (HR02/04(8:2)-W) was selected from in vitro experiments and its immunity-enhancing efficacy was evaluated in mice. After oral administration of extract to BALB/c mice for 2 weeks, nitric oxide production in the peritoneal exudate cells, natural killer cell cytotoxicity, cytokine expression in splenocytes, and total cell number of immune tissues and phenotype analysis were evaluated. Our results demonstrated that HR02/04(8:2)-W significantly enhanced the immune system by increasing natural killer cell activity, cytokine expression, and total number of cells in immune tissues. In conclusion, our study validates the role of HR02/04(8:2)-W in enhancing immunity and its potential development as a functional food.

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“…Stomach ache is often accompanied by certain symptoms including fever, vomiting, loss of appetite, inability to eat, and cramps. [13][14][15][16][17][18]. Recent documents showed that gastrointestinal problems such as stomach aches or stomach upset can be treated with medicinal plants [7].…”

Section: Introductionmentioning

confidence: 99%

Natural remedies effective on stomachache in traditional medicine

Abassi

Ghaneialvar

Shahsavari

2020

Plant Biotechnol Persa

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Stomach ache is one of the most chronic and debilitating abdominal pains. Medicinal plants are one of the most accessible sources for treating diseases like gastrointestinal disorders. In this review, we investigate and report the most important medicinal plants recommended by Persian medicine for treating stomach aches and comparing them with their proven effects in modern medicine. Gastric pain was probed in Persian medicine reliable textbooks such as Cannon of Medicine (Ibn Sina), Tibbe-Akbari (Muhammad Akbar Arzaani), The Complete Art of Medicine (Kitab Kamil as-Sinaa at-tibbiyya) (Haly Abbas), Explanation of insults and signs (Kermani) Tohfeh Al-Mo'menin (Seyed Mohammad Momen Tonekaboni), and some notes were taken. The results showed that Panicum miliaceum, Punica granatum, Solanum nigrum, Calicotome spinosa, Tamarindus indica, Cuminum cyminum, Prunus domestica, Matricaria recutita, Viola odorata, Plantago psyllium, Berberis vulgaris, Pyrus communis, Linum usitatissimum, Vitis vinifera were the most important plant sources used in treating the stomach ache according to Persian medicine. The findings of this study showed that the useful effects of many recommended plants in Persian medicine are confirmed by recent scientific researches and are reliable.

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The Synergistic Effect of Hydroalcoholic Extracts of Origanum Vulgare , Hypericum Perforatum and Their Active Components Carvacrol and Hypericin Against Staphylococcus Aureus

Cited by 40 publications

References 34 publications

Study of extraction and chemical compounds of Scrophularia striata Boiss. and Scrophularia deserti Delile using HS-SPME and GC-MS

Study of extraction and chemical compounds of Scrophularia striata Boiss. and Scrophularia deserti Delile using HS-SPME and GC-MS

Enhancement of Immune Activities of Mixtures with Sasa quelpaertensis Nakai and Ficus erecta var. sieboldii

Natural remedies effective on stomachache in traditional medicine

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