The syndemic condition of psychosocial problems related to depression among sexually transmitted infections patients

IntroductionInternal migrant Men who have sex with men (IMMSM), which has the dual identity of MSM and floating population, should be more concerned among the vulnerable groups for HIV in society. Establishing appropriate prediction models to assess the risk of HIV infection among IMMSM is of great significance to against HIV infection and transmission.MethodsHIV and syphilis infection were detected using rapid test kits, and other 30 variables were collected among IMMSM through questionnaire. Taking HIV infection status as the dependent variable, three methods were used to screen predictors and three prediction models were developed respectively. The Hosmer-Lemeshow test was performed to verify the fit of the models, and the net classification improvement and integrated discrimination improvement were used to compare these models to determine the optimal model. Based on the optimal model, a prediction nomogram was developed as an instrument to assess the risk of HIV infection among IMMSM. To quantify the predictive ability of the nomogram, the C-index measurement was performed, and internal validation was performed using bootstrap method. The receiver operating characteristic (ROC) curve, calibration plot and dynamic component analysis (DCA) were respectively performed to assess the efficacy, accuracy and clinical utility of the prediction nomogram.ResultsIn this study, 12.52% IMMSMs were tested HIV-positive and 8.0% IMMSMs were tested syphilis-positive. Model A, model B, and model C fitted well, and model B was the optimal model. A nomogram was developed based on the model B. The C-index of the nomogram was 0.757 (95% CI: 0.701–0.812), and the C-index of internal verification was 0.705.ConclusionsThe model established by stepwise selection methods incorporating 11 risk factors (age, education, marriage, monthly income, verbal violence, syphilis, score of CUSS, score of RSES, score of ULS, score of ES and score of DS) was the optimal model that achieved the best predictive power. The risk nomogram based on the optimal model had relatively good efficacy, accuracy and clinical utility in identifying internal migrant MSM at high-risk for HIV infection, which is helpful for developing targeted intervention for them.

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“…All of the above scales are widely used in the MSM population ( 25 – 40 ), and total of 31 independent variables were collected.…”

Section: Methodsmentioning

confidence: 99%

Predicting the risk of HIV infection among internal migrant MSM in China: An optimal model based on three variable selection methods

Liu

Xia²,

Wang³

et al. 2022

Front. Public Health

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“…Worldwide, more than 1 million STIs are acquired on a daily basis 1 . Beside the infection itself, STIs may cause long-term reproductive and pregnancy-related complications including infertility, 1 in addition to the psychological distress such as stigma and depression 2,3 . Chlamydia trachomatis is the most prevalent curable STI 1 .…”

mentioning

confidence: 99%

“…1 Beside the infection itself, STIs may cause long-term reproductive and pregnancy-related complications including infertility, 1 in addition to the psychological distress such as stigma and depression. 2 , 3 Chlamydia trachomatis is the most prevalent curable STI. 1 Globally, in the 30-year period from 1990 to 2019, chlamydia cases increased by 53.3%, reaching an age-standardized incident rate of 2884 per 100,000 population in 2019.…”

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confidence: 99%

Chlamydia trachomatis Seroepidemiology and Associated Factors in Fertility Treatment–Seeking Patients in the Abu Dhabi Emirate, United Arab Emirates

Abdo

Aslam²,

Suliansyah³

et al. 2023

Sexual Trans Dis

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This study was designed to investigate the seroepidemiology of and identify factors associated with exposure to Chlamydia trachomatis (C. trachomatis) in fertility treatment-seeking patients in Abu Dhabi Emirate, United Arab Emirates. Methods: A total of 308 fertility treatment-seeking patients were surveyed. Seroprevalence of past (IgG positive), current/acute (IgM positive), and active infection (IgA positive) with C. trachomatis was quantified. Factors associated with exposure to C. trachomatis were identified.Results: Overall, 19.0%, 5.2%, and 1.6% found to have past, acute/recent, and ongoing active infection with C. trachomatis, respectively. Overall, 22.0% of the patients were seropositive to any of the 3 to C. trachomatis antibodies. Male compared with female patients (45.7% vs. 18.9%, P < 0.001) and current/ex-smokers compared with nonsmokers (44.4% vs. 17.8%) had higher seropositivity. Patients with a history of pregnancy loss had higher seropositivity compared with other patients (27.0% vs. 16.8%), particularly recurrent pregnancy losses (33.3%). Current smoking (adjusted odds ratio [aOR], 3.8; 95% confidence interval, 1.32-11.04) and history of pregnancy loss (adjusted odds ratio [aOR], 3.0; 95% confidence interval, 1.5-5.8) were significantly associated with higher odds of exposure to C. trachomatis. Conclusions:The observed high seroprevalence of C. trachomatis, particularly in patients with a history of pregnancy loss, possibly indicates the contribution of C. trachomatis to the growing burden of infertility in the United Arab Emirates.

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Infektionskrankheiten

Kapfhammer¹

2022

Depression, Angst, Traumatischer Stress Und Internistische Erkrankungen

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The syndemic condition of psychosocial problems related to depression among sexually transmitted infections patients

Cited by 5 publications

References 51 publications

Predicting the risk of HIV infection among internal migrant MSM in China: An optimal model based on three variable selection methods

Predicting the risk of HIV infection among internal migrant MSM in China: An optimal model based on three variable selection methods

Chlamydia trachomatis Seroepidemiology and Associated Factors in Fertility Treatment–Seeking Patients in the Abu Dhabi Emirate, United Arab Emirates

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