The surface evoked potential and parvalbumin‐immunoreactivity in the somatosensory cortex of the developing rat

Abstract

The development of the rat somatosensory system was followed electrophysiologically and immunohistochemically. In the surface evoked potential elicited in the primary somatosensory cortex by electrical stimulation of the whisker C3 follicle, a short-latency positive wave was first recorded on postnatal Day 2. A long-latency positive wave was recorded in some pups on postnatal Day 7 and in most pups on postnatal Day 8. On postnatal Day 10, a P/N complex appeared between the short- and long-latency positive waves. Parvalbumin, believed to appear with functional maturation, appeared mainly after postnatal Day 7 in Layer V in the underlying area, although a few weakly stained cells appeared on postnatal Day 5. On postnatal Day 10, weakly stained cells appeared in the area containing barrels; their staining increased with time. In this system, electrophysiological and immunohistochemical parameters changed by the 3rd postnatal week with the most marked changes occurring within 2 postnatal weeks.

Expression of calbindin‐D28k and parvalbumin during development of rat's basolateral amygdaloid complex

“…One possible explanation of this is that PV may be connected with the formation and maturation of synapses. This explanation seems to be support by the combined electrophysiological and PV-immunohistochemical study which con®rms that PV-immunoreactivity appears with functional maturation of neurons [63].…”

Structural and Functional Aberrations in the Cerebral Cortex of Tenascin-C Deficient Mice

“…In addition, TNC deficiency may have a specific impact on the establishment of proper synaptic connections and cell type specification (see Xu et al, 2003, for origins and specification of cortical interneurons). Parvalbumin expression in a subpopulation of inhibitory neurons begins in the second postnatal week and is believed to be related to physiological maturation (Del Rio et al, 1994;Seo-Hiraiwa et al, 1995;Alcantara et al, 1996). The chemical specification of the PV subpopulation of GABAergic cortical neurons appears to be promoted by dopamine (Porter et al, 1999).…”

Dynamic patterns of colocalization of calbindin, parvalbumin and GABA in subpopulations of mouse basolateral amygdalar cells during development

“…This delayed expression of PV in some interneurons has been correlated with the functional maturation of these neurons and the formation of the inhibitory circuits (Seo-Hiraiwa et al, 1995). At present, it is not known what factors trigger the postnatal expression of PV in specific pallial interneurons, although neuronal activity appears to be necessary before a given neuron starts PV expression (Patz et al, 2004).…”