The study of efficacy of injection iron sucrose in treatment of iron deficiency anemia in pregnancy

Abstract

Background: Iron deficiency is the most common cause of anaemia in pregnancy amounting to almost 50% of pregnant ladies in India. All pregnant women, irrespective of haemoglobin status, should receive prophylactic doses of iron from second trimester. Iron sucrose has an advantage of being cost effective and readily available. The objective of this was to study the efficacy of injection Iron Sucrose in treatment of iron deficiency anaemia in pregnancy. Methods: About106 patients were given in injection iron sucrose in pregnancy, who had intolerance to oral iron or were non-compliant, in pre calculated (Ganzoni's formula) doses and were followed up with rise in hemoglobin and ferritin after 6 weeks and at term. Results: Statistically significant increase in hemoglobin levels was observed at 6 weeks after initiation of treatment (9.689±0.821 gm% vs 10.906±0.775 gm%) as well as at term (mean 10.981±0.690 gm%). The serum ferritin levels too increased significantly at term (26.7 ng/mL±12.92 vs 65.34 ng/mL±15.73). Conclusions: Present study demonstrates that iron sucrose is an excellent option to treat iron deficiency anemia in patients where oral iron therapy has either failed or not suitable. It significantly increases hemoglobin levels in the study population. It is readily available in the market and can be infused on an outpatient basis.

Differences in Ferritin and Hemoglobin Levels Before and After Administration of Iron Sucrose Injection to Second or Third Trimester Pregnant Women at Araskabu Public Health Center, Deli Serdang

“…The group that was given a total of 1000 mg of iron sucrose intravenously was divided into five doses of 200 mg each at weekly intervals, in pregnant women aged 20-24 weeks, the Hb levels were not significantly different in the group of pregnant women aged 28-32 weeks and gestational age 35-36 weeks. The study in pregnant women with different ages, gestational ages, parity, and body mass index did not differ significantly in the group receiving 200 mg iron sulfate tablets, and the group receiving 200 mg iron sucrose on alternate days by slow intravenous infusion, https://oamjms.eu/index.php/mjms/index there was significant increase in Hb levels between the two groups [36].…”