The Stent-Supported Percutaneous Angioplasty of the Carotid Artery vs. Endarterectomy Trial

Ringleb, Peter A.; Kunze, A.; Allenberg, Jens-Rainer; Hennerici, Michael G.; Jansen, O; Maurer, P.C.; Zeumer, H.; Hacke, W.

doi:10.1159/000078752

Cited by 80 publications

(41 citation statements)

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“…We are aware of 4 trials currently ongoing comparing carotid endovascular treatment with endarterectomy: the International Carotid Stenting Study (ICSS), 33 Carotid Revascularization Endarterectomy versus Stenting Trial (CREST), 34 Stent-protected Percutaneous Angioplasty of the Carotid versus Endarterectomy (SPACE), 35 and Endarterectomy versus Angioplasty in patients with Severe Symptomatic Stenosis (EVA-3S). 36 Table 2 shows the rates of outcome events for each of the included studies.…”

Section: Ongoing Trialsmentioning

confidence: 99%

Safety and Efficacy of Endovascular Treatment of Carotid Artery Stenosis Compared With Carotid Endarterectomy

Coward

Featherstone

Brown

2005

Stroke

232

146

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Background and Purpose-Endovascular treatment of atherosclerotic carotid artery stenosis may be an alternative to surgical endarterectomy. To evaluate the safety and efficacy of endovascular techniques, we conducted a systematic review of randomized studies that compared endovascular treatment with surgery for carotid stenosis. Methods-We searched the Cochrane Stroke Group trials register, the Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE, and Science Citation Index for randomized trials of carotid angioplasty and/or stenting compared with surgery. We also contacted researchers in the field and balloon catheter and stent manufacturers.

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Section: Ongoing Trialsmentioning

confidence: 99%

Safety and Efficacy of Endovascular Treatment of Carotid Artery Stenosis Compared With Carotid Endarterectomy

Coward

Featherstone

Brown

2005

Stroke

232

146

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“…The protocols in two other ongoing trials do not require cerebral protection; however, these devices may be used at the discretion of the physician. 10,19 The aforementioned trials include the International Carotid Stenting Study (CAVATAS-2) and the Stent Protected Angioplasty versus Carotid Endarterectomy trial.…”

Section: Neurosurg Focus / Volume 18 / January 2005mentioning

confidence: 99%

Procedure complications of carotid angioplasty and stent placement without cerebral protection devices

Kadkhodayan¹,

Derdeyn²,

Cross³

et al. 2005

FOC

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Object The goal in this retrospective study was to examine the procedural complication rate for carotid angioplasty and stent placement performed without cerebral protection devices. Methods Between March 1996 and December 2003, 167 carotid angioplasty and/or stent placement procedures were performed without cerebral protection devices in 152 patients (57 women and 95 men whose mean age was 64 years, range 19–92 years). Seven of these patients underwent angioplasty alone. Eighty-nine patients presented with focal neurological symptoms. Indications for surgery included atherosclerosis, radiation-associated stenosis, dissection, pseudoaneurysm, and stretched endovascular coils from aneurysm treatment. In this study, the patients' medical records were reviewed for clinical characteristics, techniques used, and resulting intraprocedural and 30-day complication rates. The intraprocedural stroke rate was four (2.4%) of 167; this included three hemispheric strokes and one retinal embolus. All events occurred in patients who had symptomatic stenosis. The procedural transient ischemic complication rate was six (3.6%) of 167, as was the procedural nonneurological complication rate. During the 30 days post-procedure, one patient had died and three had suffered permanent ischemic events (two cerebral and one ocular). The composite 30-day postprocedural stroke and death rate was eight (5%) of 160. The rate of asymptomatic angiographically confirmed abnormalities was 0.6% (one treated vessel that was occluded but asymptomatic). The 30-day rate of nonneurological complications was 2.5%. A strong association between intraprocedural thromboembolic events (eight cases) and prior ischemic symptoms was found (p = 0.01). Conclusions Carotid angioplasty and stent placement without cerebral protection devices is safe, particularly in patients without symptomatic stenosis.

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“…[66]). Aus den aktuellen Studien zur stentgeschützten Angioplastie (SPACE, EVA3S, ICCS) sind Patienten mit im Vergleich zur Bifurkationsstenose höhergradiger intracranieller Stenose ausgeschlossen worden [91].…”

Section: Methodenkritikunclassified

S3-Leitlinie Extracranielle Carotisstenose

et al. 2012

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The Stent-Supported Percutaneous Angioplasty of the Carotid Artery vs. Endarterectomy Trial

Cited by 80 publications

References 0 publications

Safety and Efficacy of Endovascular Treatment of Carotid Artery Stenosis Compared With Carotid Endarterectomy

Safety and Efficacy of Endovascular Treatment of Carotid Artery Stenosis Compared With Carotid Endarterectomy

Procedure complications of carotid angioplasty and stent placement without cerebral protection devices

S3-Leitlinie Extracranielle Carotisstenose

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