“…Despite ever increasing complexity involving the influence of sympathetic and parasympathetic systems [de Groat and Saum, 1976], it is known that below a certain pressure threshold, activation of parasympathetic efferents is ineffective, and above which, parasympathetic discharge to the bladder can be evoked following electrical stimulation of afferents in the pelvic nerves [Morrison, 1990]. In patients without neurological damage, detrusor instability (DI) is a major cause of urine loss in the female [Abrams et al, 1988]. DI is diagnosed by detection of a phasic pressure rise during cystometry.…”