The Stability of Injection of Morphine Sulphate

Foster, G. E.; Macdonald, Miss J.; Whittet, T. D.

doi:10.1111/j.2042-7158.1950.tb12986.x

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1997

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Cited by 5 publications

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“…It was also seen that the samples that were forcibly degraded by strong base and oxidation developed a brownish yellow colour at the end of the 4 days. As pseudomorphine is colourless (1,5), the above observation may support the postulation of some authors that colour development could be due to the decomposition products of pseudomorphine or other compounds (5).…”

Section: Results a N D Discussionmentioning

confidence: 50%

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Stability of morphine sulphate in saline under simulated patient administration conditions

Hor

Chan

Yow

et al. 1997

Journal of Clinical Pharmacy and Therapeutics

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confidence: 50%

“…phine-N-oxide in the ratio 9:l with a trace of a base, believed to be methylamine (1)(2)(3)(4)(5)(6)(7), is also dependent on the presence of excess oxygen (6). As the volume fill of the formulation in the mixture container is decreased, the rate of morphine loss increases substantially (8-10).…”

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confidence: 99%