The spiral hyphae of trichophyton

Davidson, A. M.; Gregory, P. H.

doi:10.1016/s0007-1536(37)80008-x

Cited by 12 publications

(2 citation statements)

References 9 publications

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“…2001 ) and the oomycete, Achlya bisexualis ( Trinci et al ., 1979 ). The formation of three-dimensional helices by hyphae has been described as right-handed for the aerial hyphae of Trichophyton species ( Davidson and Gregory, 1937 ) and the sporangiophores of Phycomyces blakesleeanus ( Trinci et al ., 1979 ). The gravitropic response of primary roots in Arabidopsis thaliana can be subverted to form right-handed helices on contact with hard-agar surfaces (reviewed by Migliaccio and Piconese, 2001 ).…”

Section: Introductionmentioning

confidence: 99%

Calcium homeostasis is required for contact‐dependent helical and sinusoidal tip growth in Candida albicans hyphae

Brand

Lee

Veses

et al. 2009

Molecular Microbiology

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SummaryHyphae of the dimorphic fungus, Candida albicans, exhibit directional tip responses when grown in contact with surfaces. On hard surfaces or in liquid media, the trajectory of hyphal growth is typically linear, with tip re-orientation events limited to encounters with topographical features (thigmotropism). In contrast, when grown on semisolid surfaces, the tips of C. albicans hyphae grow in an oscillatory manner to form regular two-dimensional sinusoidal curves and three-dimensional helices. We show that, like thigmotropism, initiation of directional tip oscillation in C. albicans hyphae is severely attenuated when Ca 2+ homeostasis is perturbed. Chelation of extracellular Ca 2+ or deletion of the Ca 2+ transporters that modulate cytosolic [Ca 2+ ] (Mid1, Cch1 or Pmr1) did not affect hyphal length but curve formation was severely reduced in mid1D and cch1D and abolished in pmr1D. Sinusoidal hypha morphology was altered in the mid1D, chs3D and heterozygous pmr1D/PMR1 strains. Treatments that affect cell wall integrity, changes in surface mannosylation or the provision of additional carbon sources had significant but less pronounced effects on oscillatory growth. The induction of twoand three-dimensional sinusoidal growth in wild-type C. albicans hyphae is therefore the consequence of mechanisms that involve Ca 2+ influx and signalling rather than gross changes in the cell wall architecture.

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Section: Introductionmentioning

confidence: 99%

Calcium homeostasis is required for contact‐dependent helical and sinusoidal tip growth in Candida albicans hyphae

Brand

Lee

Veses

et al. 2009

Molecular Microbiology

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“…The idea that hyphae may be undergoing small periodic changes in growth direction is not unprecedented as helical growth forms have been reported for many tip‐growing organisms including oomycete hyphae (Kaminskyj & Heath, 1992), fungal hyphae (Davidson & Gregory, 1937; Sherwood‐Higham et al. , 1995), and fungal sporangiophores (Trinci et al.…”

Section: Helical Growthmentioning

confidence: 99%