The specifically enhanced cellular immune responses in Pacific oyster (Crassostrea gigas) against secondary challenge with Vibrio splendidus

The modulation of extracellular superoxide dismutase in the specifically enhanced cellular immune response against secondary challenge of Vibrio splendidus in Pacific oyster (Crassostrea gigas)

“…In the same manner, the specific deduction of CgEcSOD upon the secondary V. splendidus challenge could probably inhibit the invasion of this bacteria and benefit to develop a specifically enhanced cellular immune response. The results provided a novel explanation to the specifically enhanced cellular immune responses upon the secondary challenge of V. splendidus in the previous report (Zhang et al, 2014).…”

“…In oyster, a specifically enhanced cellular immune response was also reported upon the secondary challenge of live V. splendidus (Zhang et al, 2014). As a major protein in the plasma, the concentration fluctuation and the possible roles of CgEcSOD in immune priming were investigated after twice immune stimulations in the present study.…”

“…For example, extracellular Cu-Zn SOD in ctenophore was down-regulated after a secondary homologous bacterial challenge, which was inferred as a tactics to reduce inflammatory response, saving resources and cutting down selfdamage (Bolte et al, 2013). Specifically cellular immune priming was also reported in the oysters upon the secondary challenge of live V. splendidus (Zhang et al, 2014). Further research on the roles of CgEcSOD in V. splendidus internalization and the specific priming would provide new insights into the cellular and molecular bases of the host-microorganism interactions in C. gigas.…”

“…The primary and secondary immune challenges were performed according to the previous description (Zhang et al, 2014). Ninety oysters were equally divided into two subgroups designed as FSSW (received an injection of 100 mL FSSW) and Vs (received an injection of 100 mL V. splendidus at the concentration of 2 Â 10 8 CFU mL À1 ).…”

The immune system and its modulation mechanism in scallop

“…The significantly enhanced phagocytic activity was observed in those scallops received twice stimulations [126]. In oysters, the primary stimulation of V. splendidus led to specifically enhanced phagocytosis and rapidly promoted regeneration of circulating hemocytes when the primed oysters encountered the secondary challenge with V. splendidus [129]. The increasing data favored that there are some forms of specific immune response in bivalves.…”