The spatial and temporal signatures of word production components

Abstract

This paper presents the results of a comprehensive meta-analysis of the relevant imaging literature on word production (82 experiments). In addition to the spatial overlap of activated regions, we also analyzed the available data on the time course of activations. The analysis specified regions and time windows of activation for the core processes of word production: lexical selection, phonological code retrieval, syllabification, and phonetic/articulatory preparation. A comparison of the word production results with studies on auditory word/non-word perception and reading showed that the time course of activations in word production is, on the whole, compatible with the temporal constraints that perception processes impose on the production processes they affect in picture/word interference paradigms. q 2004 Elsevier B.V. All rights reserved.Keywords: Language; Word production; Word perception; Neuroimaging The functional organization of word productionProducing spoken words, whether in isolation or in the context of a larger utterance, involves an extensive neural network. In a recent meta-analysis of 58 neuroimaging studies of word production, Indefrey and Levelt (2000) found that the main components of this network, defined as cerebral regions showing statistically distinguishable activation in word production tasks, are largely left-lateralized. In addition, different regions of activation appeared to be involved with different functional components of the word production process. For instance, the conceptually driven selection of a lexical item, as in picture naming, typically goes with activation in the mid part of the left middle temporal 0022-2860/$ -see front matter q

Altered resting‐state functional connectivity of the putamen and internal globus pallidus is related to speech impairment in Parkinson's disease

“…It is also interesting to note that, in addition to articulatory models of speech production such as DIVA, models of prearticulatory error monitoring suggest that STG may also utilize perceptual feedback in the detection of phonological errors (Indefrey & Levelt, 2004), which research has shown to be abnormal in PD (Gauvin et al., 2017; McNamara, Obler, Au, Durso, & Albert, 1992). This raises another possibility that our observed reductions in left putamen–left STG connectivity in PDSI could be linked to broader changes in the online detection and correction of speech errors in PD.…”

A perfusion fMRI investigation of thematic and categorical context effects in the spoken production of object names

“…Belke and Stielow (2013) offered an alternative interpretation of this evidence and LIFG involvement in blocked cyclic naming in terms of a top-down control mechanism operating in working memory. In addition, there is consensus that lexical-level selection processes are associated with left middle and posterior lateral temporal cortical regions, supported by more general findings for speech production tasks reviewed by Indefrey and Levelt (2004;see also Indefrey, 2011) . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 Semantic context effects 8 Surprisingly, neuroimaging, lesion and cortical stimulation investigations of the interference effect in blocked cyclic naming have typically not included presentation cycle as a factor in their analyses, and so have conflated the potentially different processes engaged between the first and subsequent cycles of the task.…”

The neural substrates for atypical planning and execution of word production in stuttering

“…This connectivity has been found to be a key path for the transformation of linguistic plan to motor commands (Indefrey and Levelt, 2004). Thus, an alteration of this connectivity directly reflects aberrant interactions between the neural substrates for atypical planning and those for execution in stuttering.…”

“…According to previous research on normal speech, the putamen is also a node of the network for phonetic encoding and syllable sequence organization during word production (Bohland and Guenther, 2006;Indefrey and Levelt, 2004). The putamen's involvement in stuttering has also been well documented.…”