The Source of Nasal Secretion in the Normal Condition: Fluorescein Tests

Ingelstedt, Sven; Ivstam, Bertel

doi:10.3109/00016484909120269

Cited by 21 publications

(6 citation statements)

References 12 publications

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“…SCHNEIDER (1660) postulated that the nasal secretions are a product of the membrane lining the nasal airways, and Ingelstedt and Ivstam (1949) showed that they are purely glandular in origin. The morphology of these glandular structures has been well described, notably by Zuckerkandl (1882), Von Heiss (1931, Schaeffer (1932), Brunner (1942) and Leonardelli, Pizzetti and Chierego (1952), and their normal variations by Proetz (1941) and Hollander (1944).…”

Section: Introductionmentioning

confidence: 99%

Histochemistry of the Nasal Respiratory Mucosa

Taylor¹

1958

J. Laryngol. Otol.

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Section: Introductionmentioning

confidence: 99%

Histochemistry of the Nasal Respiratory Mucosa

Taylor¹

1958

J. Laryngol. Otol.

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“…Conditioning of inspiratory air is one of the main functions of the nasal mucosa for protection of the lower respiratory tract 1–3 . Inspired air is heated and humidified within the short distance from the nostrils to the nasopharynx and partially cleaned of particles 4,5 .…”

mentioning

confidence: 99%

Nasal mucosal temperature during respiration

Lindemann¹,

Liu²,

Rettinger³

et al. 2002

Clin Otolaryngol

201

161

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One of the most important functions of the nose is heating the inspiratory air. The aim of the present study was to measure nasal mucosal temperature at defined intranasal sites during respiration, without interruption of nasal breathing. A total of 15 healthy volunteers was included in the study. A miniaturized thermocouple was used for continuous detection of the septal mucosal temperature in the nasal vestibule, the nasal valve area, the anterior turbinate area and the nasopharynx during respiration. The highest temperature values were measured at the end of expiration, the lowest values at the end of inspiration with a statistically significant difference (P < 0.005). Mean mucosal temperature ranged from 30.2 +/- 1.7 degrees C to 34.4 +/- 1.1 degrees C. Statistically there were significant differences between the detection sites during inspiration and expiration (P < 0.05). In our study, the temperature values of the nasal mucosa depend on the intranasal detection site and the respiratory cycle. We therefore conclude that whenever data of nasal mucosal temperature are published, it is absolutely essential to describe the precise site of detection and to give information about the time of detection in the respiratory cycle.

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“…The anterior nasal mucosa contains a relatively low amount of goblet cells, but a relatively high amount of small seromucous glands 11 . The nasal glands are known to contribute to humidification in the nose 12 and therefore the loss of nasal tissue may lead to a reduced water supply of inspiratory air in patients with septal perforations.…”

Section: Discussionmentioning

confidence: 99%

Intranasal temperature and humidity profile in patients with nasal septal perforation before and after surgical closure

et al. 2001

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Common complaints of patients with a nasal septal perforation are crusting, dryness and bleeding. As shown previously, intranasal humidity values are significantly lower in patients with a septal perforation compared with healthy volunteers. The aim of this study was to determine the influence of surgical closure of septal perforations on intranasal temperature and humidity, and to evaluate changes in clinical symptoms after surgery. Ten patients with septal perforations were included in the study. Intranasal temperature and humidity were measured at the nasal valve and anterior turbinate areas before and after surgical closure. Clinical symptoms were assessed using a nasal symptom score. The end-inspiratory humidity values were significantly (P < or = 0.05) higher postoperatively than preoperatively. The increase in temperature at the anterior turbinate area was significantly higher postoperatively. The temperature values at the nasal valve area were not significantly different. Recurrent epistaxis and nasal dryness were reduced after surgery. Nasal septal perforations disturb the intranasal temperature and humidity profile. After surgical closure, heating and humidification is improved. This may be responsible for the reduction of frequent complaints such as bleeding and dryness.

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The Source of Nasal Secretion in the Normal Condition: Fluorescein Tests

Cited by 21 publications

References 12 publications

Histochemistry of the Nasal Respiratory Mucosa

Histochemistry of the Nasal Respiratory Mucosa

Nasal mucosal temperature during respiration

Intranasal temperature and humidity profile in patients with nasal septal perforation before and after surgical closure

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