“…1), frequently designated as A and B, respectively, are isolated in the highest yields. It is now well established that these two isomers differ in their complexation behavior toward mono-and divalent cations in aqueous Solution [10] and, therefore, in their ability to extract these ions from aqueous Solution into an immiscible organic solvent [6], To date, however, most extraction studies involving DCH18C6 [14][15][16][17][18][19] have employed halogenated hydrocarbon solvents, picrate counterions, low aqueous acidities, or other experimental conditions that preclude application of the results obtained to process-scale metal ion separations, such as those involved in the treatment of acidic nuclear wastes. As a consequence, the practical Utility of these studies has been limited.…”