The Significance of Evalution of Haematocrit in Plateletpheresis Donors

Mane, Vinayak; Jagtap, Pratap; Nagane, Nitin; Dhonde, Sushma Prakash; Belwalkar, Gajanan J.; Mane, Vaibhav

doi:10.7860/jcdr/2015/8292.5746

Cited by 2 publications

(1 citation statement)

References 8 publications

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“…Due to this development, single-donor platelets acquired through automated blood collection have become increasingly popular. Apheresis is a technique used to extract one or more specific blood components, such as platelets, plasma, and stem cells, to obtain a standardized, high-quality output [2]. In the process of plateletpheresis, whole blood from a donor is processed, platelets are isolated on their own, and the remaining blood components are then given back to the donor [3].…”

Section: Introductionmentioning

confidence: 99%

Effects of plateletpheresis on hematological parameters

Setiadarma

Angela

2022

World Journal of Current Med and Pharm Research

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Apheresis for platelet concentrates has been used more frequently in recent years due to the rising demand for platelet transfusions for patients with various medical and surgical disorders. Studies on the effect of repeated or frequent plateletpheresis on the donor's hematological parameters are still limited. This article will review the effects of plateletpheresis on the donor's hematological parameters to define the proper deferral for repeat donation because this treatment is relatively new and requires early repeat donations. We systematically search the studies and review current evidence about the effects of plateletpheresis on blood parameters in healthy donors. Literature tracking was performed on PubMed, CENTRAL, EbscoHost, and ProQuest databases. There are different effects, and some studies reveal that plateletpheresis can decrease hematological parameters (HB, HCT, PLT, PDW). Some can cause an increase in hematological parameters (HB, HCT). These different effects can be caused by variable cell separator technologies, residual blood volume lost during apheresis, and mechanical hemolysis of blood in tubes by machine pumps.

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Section: Introductionmentioning

confidence: 99%

Effects of plateletpheresis on hematological parameters

Setiadarma

Angela

2022

World Journal of Current Med and Pharm Research

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The influence of the frequency of donor plasmapheresis on the concentration of ions and proteins in the blood of donors

Lamzin,

Brylyaeva,

Khapman

et al. 2024

Gematologiâ i transfuziologiâ

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Introduction. Plasmapheresis is a routine procedure in many blood centers. The most common complications in plasma donors are vasovagal and citrate reactions. The effects of citrate exposure, repeated with different frequency over a long period of time, have not been sufficiently studied.Aim. to research the effect of the frequency of plasmapheresis on the concentration of ionic and protein composition in donor blood.Materials and methods. The concentration of protein in blood serum was measured using a biochemical method. The concentration of ions was carried out using an automatic blood electrolyte analyzer. Plasma donors were divided into groups depending on gender and frequency of plasmapheresis (1–5 times a year; 6–10 times a year; 11–26 times a year). The total number of donors involved in the study was 274 (155 men and 119 women).Results. A significant decrease in the concentration of bound calcium was revealed in the group of female donors who donated plasma 11–26 times compared to the group who donated plasma 1–5 times a year. A significant decrease in the concentration of iron ions was revealed in the group of female donors who donated plasma 11–26 times compared to the group who donated plasma 1–5 times a year. Statistically significant differences in the concentrations of total protein were revealed between all three groups of male donors, and between groups of female donors who donated plasma 1–5 times and 6–10 times a year; 1–5 times and 11–26 times a year.Conclusion. The use of data on changes in the parameters of ion and protein metabolism in donors of different sexes and different donation frequencies reduces the risk of developing a citrate reaction due to the selective selection of plasma donors.

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The Significance of Evalution of Haematocrit in Plateletpheresis Donors

Cited by 2 publications

References 8 publications

Effects of plateletpheresis on hematological parameters

Effects of plateletpheresis on hematological parameters

The influence of the frequency of donor plasmapheresis on the concentration of ions and proteins in the blood of donors

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