The significance of elevated levels of parathyroid hormone in patients with morbid obesity before and after bariatric surgery

Hamoui, Nahid; Kim, Kiwan; Anthone, Gary J.; Crookes, Peter F.

doi:10.1001/archsurg.138.8.891

Cited by 110 publications

(74 citation statements)

References 9 publications

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“…Our major findings are in line with previous research that demonstrates that high PTH levels are common after gastric bypass surgery [7,8,11,15,17]. Other studies confute this finding, showing no change in calcium and vitamin D metabolism after bariatric surgery [9,22,26].…”

Section: Discussionsupporting

confidence: 92%

Risk of secondary hyperparathyroidism after laparoscopic gastric bypass surgery in obese women

et al. 2007

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Morbidly obese women have a high incidence of elevated PTH levels after gastric bypass surgery. Low vitamin D levels did not constitute the only reason behind this finding. African-American women and women older than 45 years of age were at significantly higher risk of developing secondary HPT. In these populations, aggressive supplementation with calcium citrate and vitamin D should be implemented.

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Section: Discussionsupporting

confidence: 92%

Risk of secondary hyperparathyroidism after laparoscopic gastric bypass surgery in obese women

et al. 2007

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“…For this reason individual nutritional (diet) assessment and advice is necessary both pre-and post-operatively in order to ensure that nutritional status is optimised. It is likely that most patients will require nutritional supplements of vitamins and minerals (EL 2b [37,51,131,308,310]). …”

Section: Long-term After-carementioning

confidence: 99%

Obesity surgery: Evidence-based guidelines of the European Association for Endoscopic Surgery (EAES)

Sauerland

Angrisani

Belachew³

et al. 2004

Surg Endosc

449

280

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After the patient's multidisciplinary evaluation, obesity surgery should be considered in adults with a documented BMI greater than or equal to 35 and related comorbidity, or a BMI of at least 40. In addition to standard laboratory testing, chest radiography, electrocardiography, spirometry, and abdominal ultrasonography, the preoperative evaluation of obesity surgery patients also includes upper gastrointestinal endoscopy or radiologic evaluation with a barium meal. Psychiatric consultation and polysomnography can safely be restricted to patients with clinical symptoms on preoperative screening. Adjustable gastric banding (GB), vertical banded gastroplasty (VBG), Roux-en-Y gastric bypass (RYGB) and biliopancreatic diversion (BPD) are all effective in the treatment of morbid obesity, but differ in degree of weight loss and range of complications. The choice of procedure therefore should be tailored to the individual situation. There is evidence that a laparoscopic approach is advantageous for LAGB, VBG, and GB (and probably also for BPD). Antibiotic and antithromboembolic prophylaxis should be used routinely. Patients should be seen 3 to 8 times during the first postoperative year, 1 to 4 times during the second year and once or twice a year thereafter. Outcome assessment after surgery should include weight loss and maintainance, nutritional status, comorbidities and quality-of-life.

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“…6 Additionally, this deficiency state is exacerbated after bariatric surgery. [7][8][9] Vitamin D has been linked with important anti-inflammatory and immunomodulatory roles where it regulates cytokines and profibrotic and pro-inflammatory pathways that play an important role in pain perception and propagation. [10][11][12][13][14][15] Clinically, vitamin D deficiency has been associated with chronic non-specific musculoskeletal pain syndromes and migraines.…”

Section: Résumémentioning

confidence: 99%

Low serum vitamin D levels are not associated with increased postoperative pain and opioid requirements: a historical cohort study

Bose

Khanna

You

et al. 2015

Can J Anesth/J Can Anesth

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Purpose Vitamin D deficiency has been associated with chronic non-specific musculoskeletal pain syndromes; however, studies are lacking with respect to its relationship with postoperative pain. We tested the hypothesis that a lower preoperative vitamin D level is associated with increased postoperative pain and/or opioid consumption in morbidly obese patients who had laparoscopic bariatric surgery.

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The significance of elevated levels of parathyroid hormone in patients with morbid obesity before and after bariatric surgery

Abstract: The risk of hyperparathyroidism after the duodenal switch operation is related to the length of the common channel.

Cited by 110 publications

References 9 publications

Risk of secondary hyperparathyroidism after laparoscopic gastric bypass surgery in obese women

Risk of secondary hyperparathyroidism after laparoscopic gastric bypass surgery in obese women

Obesity surgery: Evidence-based guidelines of the European Association for Endoscopic Surgery (EAES)

Low serum vitamin D levels are not associated with increased postoperative pain and opioid requirements: a historical cohort study

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