The significance of eccentric foci of hyperpigmentation ('small dark dots') within melanocytic nevi. Analysis of 59 cases

Bolognia, J. L.

doi:10.1001/archderm.130.8.1013

Cited by 18 publications

(19 citation statements)

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“…Full facial ablation with the Er:YAG laser is effective but requires antiviral prophylaxis, and the down time is prolonged. 1 Rather than ablating the entire face, the Er:YAG laser with a 2-mm spot size has been used to focally ablate only the skin overlying the osteomas, 2 but this ''large'' spot size is traumatic and puts the patient at risk of complications, including infection, scarring, and hypopigmentation. We improved upon this technique by using a 1-mm spot size.…”

Section: Successful Treatment Of Multiple Miliary Osteomas Of the Facmentioning

confidence: 99%

Letter: “Mushroom-Cloud Sign” of Melanoma

Mahlberg

Hwa

Kopf

et al. 2011

Dermatologic Surgery

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Section: Successful Treatment Of Multiple Miliary Osteomas Of the Facmentioning

confidence: 99%

Letter: “Mushroom-Cloud Sign” of Melanoma

Mahlberg

Hwa

Kopf

et al. 2011

Dermatologic Surgery

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“… 19,20 For example, Bolognia et al . reported that eccentric foci of hyperpigmentation within a melanocytic naevus may indicate the presence of melanoma 21 . Hence, if a small dark focus is noted within a melanocytic lesion, further histological sectioning of this area of hyperpigmentation may be warranted and the pathologist should be asked to section through it (Fig.…”

Section: Seven Common Scenarios Leading To Misdiagnosis Of Melanomamentioning

confidence: 99%

The most common challenges in melanoma diagnosis and how to avoid them

et al. 2009

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Due to its particularly lethal nature and tendency to affect relatively young individuals, the timely diagnosis of melanoma remains of paramount importance for clinicians and their patients. Unfortunately, melanomas can mimic benign lesions that are overwhelmingly more common in the population than are melanomas, and misdiagnosis or delay in diagnosis of melanoma can occur. Misdiagnosis of melanoma serves as one of the most common causes for malpractice litigation brought against medical practitioners. In this review we describe seven clinical scenarios that represent challenges in melanoma diagnosis and discuss potential strategies for avoiding the errors that commonly give rise to those scenarios.

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“…Alerting the histopathologist to unusual foci, such as light areas (possible regression) or dark spots, is also important. Most ‘black dots’ within nevi have been shown to be benign foci of hyperpigmentation; however, a small percent represent melanoma 50 . In such instances, if we have been alerted to the presence of a dark spot, we can order deeper sections until we find it or until the specimen block has been exhausted.…”

Section: Russian Roulette?mentioning

confidence: 99%