Letter: “Mushroom-Cloud Sign” of Melanoma

Mahlberg, Matthew J.; Hwa, Charlotte; Kopf, Alfred W.; Stein, Jennifer A.

doi:10.1111/j.1524-4725.2011.02111.x

Cited by 4 publications

(4 citation statements)

References 12 publications

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“…[5], to be a potential early sign of transformation of a nevus into a melanoma. Among all the dermoscopic descriptors of the melanoma, including the MIS, the “mushroom-cloud sign” [6] is also mentioned. This term represents the hyperpigmented area which has extended in one direction, beyond the border of the lesion, and the plume underneath represents the stalk-like projection [6].…”

Section: Discussionmentioning

confidence: 99%

“…Among all the dermoscopic descriptors of the melanoma, including the MIS, the “mushroom-cloud sign” [6] is also mentioned. This term represents the hyperpigmented area which has extended in one direction, beyond the border of the lesion, and the plume underneath represents the stalk-like projection [6]. According to Bowling [7], the presence of irregular streaks at one polar end, eccentric hyperpigmentation as a combination of eccentric atypical network, irregular globules and blotches may also be seen in invasive melanomas as a lesion of no more than 5 mm in size [7].…”

Section: Discussionmentioning

confidence: 99%

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“Mistletoe sign”: probably a new dermoscopic descriptor for melanoma in situ and melanocytic junctional nevus in the inflammatory stage

Kamińska‐Winciorek¹,

Właszczuk²,

Wydmański³

2013

pdia

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Melanomas in situ (MIS) are difficult to diagnose as they lack well-established, dermoscopic descriptors. In numerous clinical cases, there are no definitive differentiating criteria between atypical nevus and melanoma in situ. So far, no digital dermoscopic criteria have been developed which can clearly distinguish atypical naevi from MIS. It is necessary to search for predictors of MIS and clinically suspected skin lesions in dermoscopy. We present 2 patients diagnosed with and treated for melanoma in situ and junctional nevus in its inflammatory stage. This includes a new morphological structure in dermoscopy known as the “mistletoe sign”. Below, we have described dermoscopic pictures, with appropriate histopathology, for patients with the “mistletoe sign”. Dermoscopy in two cases revealed multiple, well-circumscribed areas, consisting of non-uniform, sometimes pseudo-dichotomously branched structures, mimicking pseudopods, which were not reticular, arising from overall reticular or homogenous patterns resembling the mistletoe. Due to the fact that this is one of the several reports of its kind, further research and observation are still necessary. The “mistletoe sign” may be a descriptor of the melanocytic nevus in the inflammatory stage and the melanoma in situ; however, further studies are necessary.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“Mistletoe sign”: probably a new dermoscopic descriptor for melanoma in situ and melanocytic junctional nevus in the inflammatory stage

Kamińska‐Winciorek¹,

Właszczuk²,

Wydmański³

2013

pdia

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“…This term also combines features of melanoma specifically, asymmetry, irregular border, and multiple colors. 30…”

Section: Mushroom Cloud Signmentioning

confidence: 99%

Evolving eponymous signs in diagnostic dermoscopy

Bothra¹,

Das²,

Maheswari³

et al. 2021

IJCED

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Dermoscopy is a very useful technique devised for an earlier diagnosis of skin melanoma with a clinic-pathological correlation. Later it was found to be beneficial for the diagnosis of many other pigmented skin lesions, such as seborrheic keratosis, pigmented basal cell carcinoma, hemangioma, blue nevus, atypical nevus, and mole, which can often clinically simulate melanoma. Of late, its use in general clinical dermatology is growing with the recognition of new and specific patterns in conditions such as hair disorders, inflammatory disorders, and infections/infestation. It is still in the evolving phase and many new signs are described presently. Eponyms are used almost daily in dermatology practice. The eponyms in dermoscopy, trichoscopy, and onychoscopy are based on the imaginative capability of the authors and they have been very much successful in describing them. It becomes easier to memorize and identify the various appearances for early diagnosis and management. In this article we attempt to highlight the various dermoscopic signs described in dermatology.

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“…Once past the border, a faint stalk-like projection can be seen. 79 The ''mistletoe sign'' represents well-circumscribed areas with nonuniform structures resembling branching pseudopods. This pattern arises from reticular or homogenous background patterns, which are reminiscent of mistletoe.…”

Section: Clinical Features Key Pointsmentioning

confidence: 99%